Deoxyribonuclease Activity and Deoxyribonucleic Acid Synthesis in Normal, Regenerating, Precancerous and Cancerous Rat Liver

INCREASE in the rate of deoxyribonucleic acid synthesis is a biochemical characteristic of hyperplastic growth. Whereas the rate of growth under normal conditions is under rigorous control, malignant growth may be characterized by the impairment of this kind of control. Since deoxyribonucleic acid s...

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Veröffentlicht in:	Nature (London) 1958-11, Vol.182 (4646), p.1386-1387
1. Verfasser:	BRODY, SAM
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Deoxyribonucleases DNA - metabolism DNA Replication Humanities and Social Sciences letter Liver - metabolism Liver Neoplasms Liver Neoplasms, Experimental multidisciplinary Old Medline Rats Science Science (multidisciplinary)
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description	INCREASE in the rate of deoxyribonucleic acid synthesis is a biochemical characteristic of hyperplastic growth. Whereas the rate of growth under normal conditions is under rigorous control, malignant growth may be characterized by the impairment of this kind of control. Since deoxyribonucleic acid synthesis is necessary for cell division, it is possible that this control may be exercised by the regulation, of deoxyribonucleic acid metabolism. The purpose of this communication is to direct attention to a number of observations which, taken together, seem to indicate that deoxyribonuclease may be involved in such regulation.
doi_str_mv	10.1038/1821386b0
format	Article
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Whereas the rate of growth under normal conditions is under rigorous control, malignant growth may be characterized by the impairment of this kind of control. Since deoxyribonucleic acid synthesis is necessary for cell division, it is possible that this control may be exercised by the regulation, of deoxyribonucleic acid metabolism. 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subjects	Animals Deoxyribonucleases DNA - metabolism DNA Replication Humanities and Social Sciences letter Liver - metabolism Liver Neoplasms Liver Neoplasms, Experimental multidisciplinary Old Medline Rats Science Science (multidisciplinary)
title	Deoxyribonuclease Activity and Deoxyribonucleic Acid Synthesis in Normal, Regenerating, Precancerous and Cancerous Rat Liver
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