Drugs and Group Psychotherapy in Neurotic Depression
Chronically depressed neurotic women outpatients were randomly assigned, after a two-week placebo washout period, to receive one of three medications (imipramine, diazepam, or placebo) and to either weekly group psychotherapy or biweekly brief supportive sessions at one of two clinics. Analyses of c...
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| Veröffentlicht in: | The American journal of psychiatry 1974-02, Vol.131 (2), p.191-198 |
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| container_title | The American journal of psychiatry |
| container_volume | 131 |
| creator | COVI, LINO LIPMAN, RONALD S DEROGATES, LEONARD R SMITH, JAMES E PATTISON, JOSEPH H |
| description | Chronically depressed neurotic women outpatients were randomly assigned, after a two-week placebo washout period, to receive one of three medications (imipramine, diazepam, or placebo) and to either weekly group psychotherapy or biweekly brief supportive sessions at one of two clinics. Analyses of covariance for the first 16 weeks of active treatment (N = 146) indicated a marked therapeutic advantage for imipramine on most of the outcome measures. No advantage for group therapy was detected on these measures. Patients who showed improvement were continued in further controlled drug treatment for up to a total of 71 weeks; preliminary analyses of this phase showed some continuing advantage for treatment with imipramine. |
| doi_str_mv | 10.1176/ajp.131.2.191 |
| format | Article |
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Analyses of covariance for the first 16 weeks of active treatment (N = 146) indicated a marked therapeutic advantage for imipramine on most of the outcome measures. No advantage for group therapy was detected on these measures. Patients who showed improvement were continued in further controlled drug treatment for up to a total of 71 weeks; preliminary analyses of this phase showed some continuing advantage for treatment with imipramine.</description><identifier>ISSN: 0002-953X</identifier><identifier>EISSN: 1535-7228</identifier><identifier>DOI: 10.1176/ajp.131.2.191</identifier><identifier>PMID: 4587808</identifier><language>eng</language><publisher>United States: American Psychiatric Publishing</publisher><subject>Adult ; Chronic Disease ; Clinical Trials as Topic ; Depression - classification ; Depression - therapy ; Diazepam - administration & dosage ; Diazepam - therapeutic use ; Drug Evaluation ; Female ; Humans ; Imipramine - administration & dosage ; Imipramine - therapeutic use ; Middle Aged ; Outpatient Clinics, Hospital ; Placebos ; Psychiatric Status Rating Scales ; Psychotherapy, Brief ; Psychotherapy, Group ; Remission, Spontaneous</subject><ispartof>The American journal of psychiatry, 1974-02, Vol.131 (2), p.191-198</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a351t-acca70756ca5d9c99642bb5253cc55dc31bfc5d4999e919e7e07c589ba018bde3</citedby><cites>FETCH-LOGICAL-a351t-acca70756ca5d9c99642bb5253cc55dc31bfc5d4999e919e7e07c589ba018bde3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://psychiatryonline.org/doi/epdf/10.1176/ajp.131.2.191$$EPDF$$P50$$Gappi$$H</linktopdf><linktohtml>$$Uhttps://psychiatryonline.org/doi/full/10.1176/ajp.131.2.191$$EHTML$$P50$$Gappi$$H</linktohtml><link.rule.ids>314,776,780,2846,21610,27848,27903,27904,77536,77537</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4587808$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>COVI, LINO</creatorcontrib><creatorcontrib>LIPMAN, RONALD S</creatorcontrib><creatorcontrib>DEROGATES, LEONARD R</creatorcontrib><creatorcontrib>SMITH, JAMES E</creatorcontrib><creatorcontrib>PATTISON, JOSEPH H</creatorcontrib><title>Drugs and Group Psychotherapy in Neurotic Depression</title><title>The American journal of psychiatry</title><addtitle>Am J Psychiatry</addtitle><description>Chronically depressed neurotic women outpatients were randomly assigned, after a two-week placebo washout period, to receive one of three medications (imipramine, diazepam, or placebo) and to either weekly group psychotherapy or biweekly brief supportive sessions at one of two clinics. 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Patients who showed improvement were continued in further controlled drug treatment for up to a total of 71 weeks; preliminary analyses of this phase showed some continuing advantage for treatment with imipramine.</description><subject>Adult</subject><subject>Chronic Disease</subject><subject>Clinical Trials as Topic</subject><subject>Depression - classification</subject><subject>Depression - therapy</subject><subject>Diazepam - administration & dosage</subject><subject>Diazepam - therapeutic use</subject><subject>Drug Evaluation</subject><subject>Female</subject><subject>Humans</subject><subject>Imipramine - administration & dosage</subject><subject>Imipramine - therapeutic use</subject><subject>Middle Aged</subject><subject>Outpatient Clinics, Hospital</subject><subject>Placebos</subject><subject>Psychiatric Status Rating Scales</subject><subject>Psychotherapy, Brief</subject><subject>Psychotherapy, Group</subject><subject>Remission, Spontaneous</subject><issn>0002-953X</issn><issn>1535-7228</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1974</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>K30</sourceid><recordid>eNptkE1LAzEQhoMotVaPHoUFoQdh13xsNslRWq1CUQ8K3kI2m9ot7SYmm0P_vSktIuJpGOaZd4YHgEsEC4RYdatWrkAEFbhAAh2BIaKE5gxjfgyGEEKcC0o-TsFZCKvUQsLwAAxKyhmHfAjKqY-fIVNdk828jS57DVu9tP3SeOW2WdtlzyZ627c6mxrnTQit7c7ByUKtg7k41BF4f7h_mzzm85fZ0-RunitCUZ8rrRWDjFZa0UZoIaoS1zXFlGhNaaMJqheaNqUQwggkDDOQacpFrSDidWPICIz3uc7br2hCLzdt0Ga9Vp2xMUiOMS4Z4gm8_gOubPRd-k0mNbCChFc0Ufme0t6G4M1COt9ulN9KBOXOpUwudwsSy-Qy8VeH1FhvTPNDH-Sl-c1-rpxrf138N-wb42x8Dw</recordid><startdate>197402</startdate><enddate>197402</enddate><creator>COVI, LINO</creator><creator>LIPMAN, RONALD S</creator><creator>DEROGATES, LEONARD R</creator><creator>SMITH, JAMES E</creator><creator>PATTISON, JOSEPH H</creator><general>American Psychiatric Publishing</general><general>American Psychiatric Association</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>HAWNG</scope><scope>HBMBR</scope><scope>IBDFT</scope><scope>K30</scope><scope>PAAUG</scope><scope>PAWHS</scope><scope>PAWZZ</scope><scope>PAXOH</scope><scope>PBHAV</scope><scope>PBQSW</scope><scope>PBYQZ</scope><scope>PCIWU</scope><scope>PCMID</scope><scope>PCZJX</scope><scope>PDGRG</scope><scope>PDWWI</scope><scope>PETMR</scope><scope>PFVGT</scope><scope>PGXDX</scope><scope>PIHIL</scope><scope>PISVA</scope><scope>PJCTQ</scope><scope>PJTMS</scope><scope>PLCHJ</scope><scope>PMHAD</scope><scope>PNQDJ</scope><scope>POUND</scope><scope>PPLAD</scope><scope>PQAPC</scope><scope>PQCAN</scope><scope>PQCMW</scope><scope>PQEME</scope><scope>PQHKH</scope><scope>PQMID</scope><scope>PQNCT</scope><scope>PQNET</scope><scope>PQSCT</scope><scope>PQSET</scope><scope>PSVJG</scope><scope>PVMQY</scope><scope>PZGFC</scope><scope>7X8</scope></search><sort><creationdate>197402</creationdate><title>Drugs and Group Psychotherapy in Neurotic Depression</title><author>COVI, LINO ; LIPMAN, RONALD S ; DEROGATES, LEONARD R ; SMITH, JAMES E ; PATTISON, JOSEPH H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a351t-acca70756ca5d9c99642bb5253cc55dc31bfc5d4999e919e7e07c589ba018bde3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1974</creationdate><topic>Adult</topic><topic>Chronic Disease</topic><topic>Clinical Trials as Topic</topic><topic>Depression - 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| fulltext | fulltext |
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| ispartof | The American journal of psychiatry, 1974-02, Vol.131 (2), p.191-198 |
| issn | 0002-953X 1535-7228 |
| language | eng |
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| source | MEDLINE; Psychiatry Legacy Collection Online Journals 1844-1996; Periodicals Index Online |
| subjects | Adult Chronic Disease Clinical Trials as Topic Depression - classification Depression - therapy Diazepam - administration & dosage Diazepam - therapeutic use Drug Evaluation Female Humans Imipramine - administration & dosage Imipramine - therapeutic use Middle Aged Outpatient Clinics, Hospital Placebos Psychiatric Status Rating Scales Psychotherapy, Brief Psychotherapy, Group Remission, Spontaneous |
| title | Drugs and Group Psychotherapy in Neurotic Depression |
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