Disease Course Patterns After Discontinuation of Bevacizumab: Pooled Analysis of Randomized Phase III Trials

Preclinical studies have suggested accelerated tumor growth, local invasion, and distant metastasis after withdrawal of treatment with some antiangiogenic agents. To investigate whether discontinuation of bevacizumab treatment is associated with accelerated disease progression or increased mortality...

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Veröffentlicht in:	Journal of clinical oncology 2011-01, Vol.29 (1), p.83-88
Hauptverfasser:	MILES, David, HARBECK, Nadia, ESCUDIER, Bernard, HURWITZ, Herbert, SALTZ, Leonard, VAN CUTSEM, Eric, CASSIDY, Jim, MUELLER, Barbara, SIRZEN, Florin
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Monoclonal - administration & dosage Antibodies, Monoclonal - adverse effects Antibodies, Monoclonal, Humanized Bevacizumab Biological and medical sciences Clinical Trials, Phase III as Topic Disease Progression Disease-Free Survival Humans Medical sciences Neoplasms - drug therapy Randomized Controlled Trials as Topic Retrospective Studies Tumors
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