The extractability of the Duquénois-positive cannabinoids
A comparison was made of the efficiency with which a number of organic solvents and water extract the Duquénois-positive fraction of cannabinoids from the dried plant Cannabis sativa L. It was determined that alcohols are generally more effective than most other solvents in removing these compounds....
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| Veröffentlicht in: | Toxicology (Amsterdam) 1973-12, Vol.1 (4), p.289-300 |
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| container_title | Toxicology (Amsterdam) |
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| creator | Duke, Eleanor L. Reimann, Bernhard E.F. |
| description | A comparison was made of the efficiency with which a number of organic solvents and water extract the Duquénois-positive fraction of cannabinoids from the dried plant
Cannabis sativa L.
It was determined that alcohols are generally more effective than most other solvents in removing these compounds. These findings are compared and discussed with the results of other investigators.
Hot water was found to extract only about 0.002% of cannabinoids present (0.25 g plant material yields about 3–5 μg cannabinoids). The human toxicity level of cannabinoids is discussed with respect to reported severe pathological reactions after i.v. injection of the plant decoctions. It is suggested that secondary plant products other than the cannabinoids may be responsible for the severe physiological reactions. |
| doi_str_mv | 10.1016/0300-483X(73)90035-8 |
| format | Article |
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Cannabis sativa L.
It was determined that alcohols are generally more effective than most other solvents in removing these compounds. These findings are compared and discussed with the results of other investigators.
Hot water was found to extract only about 0.002% of cannabinoids present (0.25 g plant material yields about 3–5 μg cannabinoids). The human toxicity level of cannabinoids is discussed with respect to reported severe pathological reactions after i.v. injection of the plant decoctions. It is suggested that secondary plant products other than the cannabinoids may be responsible for the severe physiological reactions.</description><identifier>ISSN: 0300-483X</identifier><identifier>EISSN: 1879-3185</identifier><identifier>DOI: 10.1016/0300-483X(73)90035-8</identifier><identifier>PMID: 4781150</identifier><language>eng</language><publisher>Ireland: Elsevier Ireland Ltd</publisher><subject>Alcohols ; Amines ; Cannabis - isolation & purification ; Chemical Phenomena ; Chemistry ; Esters ; Ethers ; Hydrocarbons ; Hydrocarbons, Halogenated ; Indicators and Reagents ; Ketones ; Methods ; Solubility ; Solvents ; Water</subject><ispartof>Toxicology (Amsterdam), 1973-12, Vol.1 (4), p.289-300</ispartof><rights>1973</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c221t-c45a52ab10108ecd17f01519b3c41c88d1cd6980b71ca157b87eab32598ad0b33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0300-483X(73)90035-8$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4781150$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Duke, Eleanor L.</creatorcontrib><creatorcontrib>Reimann, Bernhard E.F.</creatorcontrib><title>The extractability of the Duquénois-positive cannabinoids</title><title>Toxicology (Amsterdam)</title><addtitle>Toxicology</addtitle><description>A comparison was made of the efficiency with which a number of organic solvents and water extract the Duquénois-positive fraction of cannabinoids from the dried plant
Cannabis sativa L.
It was determined that alcohols are generally more effective than most other solvents in removing these compounds. These findings are compared and discussed with the results of other investigators.
Hot water was found to extract only about 0.002% of cannabinoids present (0.25 g plant material yields about 3–5 μg cannabinoids). The human toxicity level of cannabinoids is discussed with respect to reported severe pathological reactions after i.v. injection of the plant decoctions. It is suggested that secondary plant products other than the cannabinoids may be responsible for the severe physiological reactions.</description><subject>Alcohols</subject><subject>Amines</subject><subject>Cannabis - isolation & purification</subject><subject>Chemical Phenomena</subject><subject>Chemistry</subject><subject>Esters</subject><subject>Ethers</subject><subject>Hydrocarbons</subject><subject>Hydrocarbons, Halogenated</subject><subject>Indicators and Reagents</subject><subject>Ketones</subject><subject>Methods</subject><subject>Solubility</subject><subject>Solvents</subject><subject>Water</subject><issn>0300-483X</issn><issn>1879-3185</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1973</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kM9KAzEQxoMotVbfQGFPoofVzGazyXoQpP6FgpcK3kI2yWJku9sm2WIfyefwxUxt6dHTwHzffDPzQ-gU8BVgKK4xwTjNOXm_YOSyxJjQlO-hIXBWpgQ43UfDneUQHXn_iTHOSF4M0CBnHIDiIbqZfpjEfAUnVZCVbWxYJV2dhNi97xf9z3fbWZ_OO2-DXZpEybaNttjU_hgd1LLx5mRbR-jt8WE6fk4nr08v47tJqrIMQqpyKmkmq3gz5kZpYDUGCmVFVA6Kcw1KFyXHFQMlgbKKMyMrktGSS40rQkbofJM7d92iNz6ImfXKNI1sTdd7wTMos7IoojHfGJXrvHemFnNnZ9KtBGCxRibWPMSah2BE_CETPI6dbfP7amb0bmjLKOq3G93EJ5fWOOGVNa0y2jqjgtCd_X_BL_Lpe10</recordid><startdate>197312</startdate><enddate>197312</enddate><creator>Duke, Eleanor L.</creator><creator>Reimann, Bernhard E.F.</creator><general>Elsevier Ireland Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197312</creationdate><title>The extractability of the Duquénois-positive cannabinoids</title><author>Duke, Eleanor L. ; Reimann, Bernhard E.F.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c221t-c45a52ab10108ecd17f01519b3c41c88d1cd6980b71ca157b87eab32598ad0b33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1973</creationdate><topic>Alcohols</topic><topic>Amines</topic><topic>Cannabis - isolation & purification</topic><topic>Chemical Phenomena</topic><topic>Chemistry</topic><topic>Esters</topic><topic>Ethers</topic><topic>Hydrocarbons</topic><topic>Hydrocarbons, Halogenated</topic><topic>Indicators and Reagents</topic><topic>Ketones</topic><topic>Methods</topic><topic>Solubility</topic><topic>Solvents</topic><topic>Water</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Duke, Eleanor L.</creatorcontrib><creatorcontrib>Reimann, Bernhard E.F.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Toxicology (Amsterdam)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Duke, Eleanor L.</au><au>Reimann, Bernhard E.F.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The extractability of the Duquénois-positive cannabinoids</atitle><jtitle>Toxicology (Amsterdam)</jtitle><addtitle>Toxicology</addtitle><date>1973-12</date><risdate>1973</risdate><volume>1</volume><issue>4</issue><spage>289</spage><epage>300</epage><pages>289-300</pages><issn>0300-483X</issn><eissn>1879-3185</eissn><abstract>A comparison was made of the efficiency with which a number of organic solvents and water extract the Duquénois-positive fraction of cannabinoids from the dried plant
Cannabis sativa L.
It was determined that alcohols are generally more effective than most other solvents in removing these compounds. These findings are compared and discussed with the results of other investigators.
Hot water was found to extract only about 0.002% of cannabinoids present (0.25 g plant material yields about 3–5 μg cannabinoids). The human toxicity level of cannabinoids is discussed with respect to reported severe pathological reactions after i.v. injection of the plant decoctions. It is suggested that secondary plant products other than the cannabinoids may be responsible for the severe physiological reactions.</abstract><cop>Ireland</cop><pub>Elsevier Ireland Ltd</pub><pmid>4781150</pmid><doi>10.1016/0300-483X(73)90035-8</doi><tpages>12</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0300-483X |
| ispartof | Toxicology (Amsterdam), 1973-12, Vol.1 (4), p.289-300 |
| issn | 0300-483X 1879-3185 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Alcohols Amines Cannabis - isolation & purification Chemical Phenomena Chemistry Esters Ethers Hydrocarbons Hydrocarbons, Halogenated Indicators and Reagents Ketones Methods Solubility Solvents Water |
| title | The extractability of the Duquénois-positive cannabinoids |
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