Recent Trends in the Incidence, Treatment, and Outcomes of Patients with STEMI and NSTEMI
Abstract Background Despite the widespread use of electrocardiographic changes to characterize patients presenting with acute myocardial infarction, little is known about recent trends in the incidence rates, treatment, and outcomes of patients admitted for acute myocardial infarction further classi...
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| Veröffentlicht in: | The American journal of medicine 2011, Vol.124 (1), p.40-47 |
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| creator | McManus, David D., MD, FACC Gore, Joel, MD, FACC Yarzebski, Jorge, MD, MPH Spencer, Frederick, MD Lessard, Darleen, MS Goldberg, Robert J., PhD |
| description | Abstract Background Despite the widespread use of electrocardiographic changes to characterize patients presenting with acute myocardial infarction, little is known about recent trends in the incidence rates, treatment, and outcomes of patients admitted for acute myocardial infarction further classified according to the presence of ST-segment elevation. The objectives of this population-based study were to examine recent trends in the incidence and death rates associated with the 2 major types of acute myocardial infarction in residents of a large central Massachusetts metropolitan area. Methods We reviewed the medical records of 5383 residents of the Worcester (MA) metropolitan area hospitalized for either ST-segment elevation acute myocardial infarction (STEMI) or non-ST-segment acute myocardial infarction (NSTEMI) between 1997 and 2005 at 11 greater Worcester medical centers. Results The incidence rates (per 100,000) of STEMI decreased appreciably (121 to 77), whereas the incidence rates of NSTEMI increased slightly (126 to 132) between 1997 and 2005. Although in-hospital and 30-day case-fatality rates remained stable in both groups, 1-year postdischarge death rates decreased between 1997 and 2005 for patients with STEMI and NSTEMI. Conclusions The results of this study demonstrate recent decreases in the magnitude of STEMI, slight increases in the incidence rates of NSTEMI, and decreases in long-term mortality in patients with STEMI and NSTEMI. Our findings suggest that acute myocardial infarction prevention and treatment efforts have resulted in favorable decreases in the frequency of STEMI and death rates from the major types of acute myocardial infarction. |
| doi_str_mv | 10.1016/j.amjmed.2010.07.023 |
| format | Article |
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The objectives of this population-based study were to examine recent trends in the incidence and death rates associated with the 2 major types of acute myocardial infarction in residents of a large central Massachusetts metropolitan area. Methods We reviewed the medical records of 5383 residents of the Worcester (MA) metropolitan area hospitalized for either ST-segment elevation acute myocardial infarction (STEMI) or non-ST-segment acute myocardial infarction (NSTEMI) between 1997 and 2005 at 11 greater Worcester medical centers. Results The incidence rates (per 100,000) of STEMI decreased appreciably (121 to 77), whereas the incidence rates of NSTEMI increased slightly (126 to 132) between 1997 and 2005. Although in-hospital and 30-day case-fatality rates remained stable in both groups, 1-year postdischarge death rates decreased between 1997 and 2005 for patients with STEMI and NSTEMI. Conclusions The results of this study demonstrate recent decreases in the magnitude of STEMI, slight increases in the incidence rates of NSTEMI, and decreases in long-term mortality in patients with STEMI and NSTEMI. Our findings suggest that acute myocardial infarction prevention and treatment efforts have resulted in favorable decreases in the frequency of STEMI and death rates from the major types of acute myocardial infarction.</description><identifier>ISSN: 0002-9343</identifier><identifier>EISSN: 1555-7162</identifier><identifier>DOI: 10.1016/j.amjmed.2010.07.023</identifier><identifier>PMID: 21187184</identifier><identifier>CODEN: AJMEAZ</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Acute myocardial infarction ; Adult ; Aged ; Biological and medical sciences ; Cardiology. Vascular system ; Clinical outcomes ; Coronary heart disease ; Electrocardiography ; Epidemiology ; Female ; General aspects ; Heart ; Heart attacks ; Hospital Mortality ; Hospitalization - statistics & numerical data ; Hospitalization - trends ; Humans ; Incidence ; Internal Medicine ; Male ; Medical prognosis ; Medical sciences ; Medical treatment ; Middle Aged ; Mortality ; Myocardial Infarction - epidemiology ; Myocardial Infarction - mortality ; Myocardial Infarction - therapy ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Trends in incidence and prognosis</subject><ispartof>The American journal of medicine, 2011, Vol.124 (1), p.40-47</ispartof><rights>Elsevier Inc.</rights><rights>2011 Elsevier Inc.</rights><rights>2015 INIST-CNRS</rights><rights>2011 Elsevier Inc. All rights reserved.</rights><rights>Copyright Elsevier Sequoia S.A. Jan 2011</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c519t-36f18f31cbee73df590d68e1511a0aeaf57ab39d096226314609eff0e1dd0e1f3</citedby><cites>FETCH-LOGICAL-c519t-36f18f31cbee73df590d68e1511a0aeaf57ab39d096226314609eff0e1dd0e1f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0002934310007369$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,4010,27900,27901,27902,65534</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=23784968$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21187184$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>McManus, David D., MD, FACC</creatorcontrib><creatorcontrib>Gore, Joel, MD, FACC</creatorcontrib><creatorcontrib>Yarzebski, Jorge, MD, MPH</creatorcontrib><creatorcontrib>Spencer, Frederick, MD</creatorcontrib><creatorcontrib>Lessard, Darleen, MS</creatorcontrib><creatorcontrib>Goldberg, Robert J., PhD</creatorcontrib><title>Recent Trends in the Incidence, Treatment, and Outcomes of Patients with STEMI and NSTEMI</title><title>The American journal of medicine</title><addtitle>Am J Med</addtitle><description>Abstract Background Despite the widespread use of electrocardiographic changes to characterize patients presenting with acute myocardial infarction, little is known about recent trends in the incidence rates, treatment, and outcomes of patients admitted for acute myocardial infarction further classified according to the presence of ST-segment elevation. The objectives of this population-based study were to examine recent trends in the incidence and death rates associated with the 2 major types of acute myocardial infarction in residents of a large central Massachusetts metropolitan area. Methods We reviewed the medical records of 5383 residents of the Worcester (MA) metropolitan area hospitalized for either ST-segment elevation acute myocardial infarction (STEMI) or non-ST-segment acute myocardial infarction (NSTEMI) between 1997 and 2005 at 11 greater Worcester medical centers. Results The incidence rates (per 100,000) of STEMI decreased appreciably (121 to 77), whereas the incidence rates of NSTEMI increased slightly (126 to 132) between 1997 and 2005. Although in-hospital and 30-day case-fatality rates remained stable in both groups, 1-year postdischarge death rates decreased between 1997 and 2005 for patients with STEMI and NSTEMI. Conclusions The results of this study demonstrate recent decreases in the magnitude of STEMI, slight increases in the incidence rates of NSTEMI, and decreases in long-term mortality in patients with STEMI and NSTEMI. Our findings suggest that acute myocardial infarction prevention and treatment efforts have resulted in favorable decreases in the frequency of STEMI and death rates from the major types of acute myocardial infarction.</description><subject>Acute myocardial infarction</subject><subject>Adult</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Cardiology. Vascular system</subject><subject>Clinical outcomes</subject><subject>Coronary heart disease</subject><subject>Electrocardiography</subject><subject>Epidemiology</subject><subject>Female</subject><subject>General aspects</subject><subject>Heart</subject><subject>Heart attacks</subject><subject>Hospital Mortality</subject><subject>Hospitalization - statistics & numerical data</subject><subject>Hospitalization - trends</subject><subject>Humans</subject><subject>Incidence</subject><subject>Internal Medicine</subject><subject>Male</subject><subject>Medical prognosis</subject><subject>Medical sciences</subject><subject>Medical treatment</subject><subject>Middle Aged</subject><subject>Mortality</subject><subject>Myocardial Infarction - epidemiology</subject><subject>Myocardial Infarction - mortality</subject><subject>Myocardial Infarction - therapy</subject><subject>Public health. Hygiene</subject><subject>Public health. Hygiene-occupational medicine</subject><subject>Trends in incidence and prognosis</subject><issn>0002-9343</issn><issn>1555-7162</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkk1v1DAQhi0EokvhHyBkISEuzeKJYye-IKGqwEqFIrocOFlee6w65KPYCaj_Hqe7BakXLvbY88yHXw8hz4GtgYF8065N3_bo1iXLV6xes5I_ICsQQhQ1yPIhWTHGykLxih-RJym1-ciUkI_JUQnQ1NBUK_L9K1ocJrqNOLhEw0CnK6SbwQaHg8WTxWGmPiMn1AyOXsyTHXtMdPT0i5lCdiT6O0xX9HJ79mlzy3y-NZ-SR950CZ8d9mPy7f3Z9vRjcX7xYXP67rywAtRUcOmh8RzsDrHmzgvFnGwQBIBhBo0Xtdlx5ZiSZSk5VJIp9J4hOJcXz4_J633e6zj-nDFNug_JYteZAcc56aYEoUSlIJMv75HtOMchN6ebqq4allXJULWHbBxTiuj1dQy9iTcamF6E163eC68X4TWrdRY-h7045J53i-8u6E7pDLw6ACZZ0_lossbpH8frplJyqf92z2HW7FfAqJMNy1e4ENFO2o3hf53cT2C7MIRc8wfeYPr7ZNCp1ExfLkOyzAhko-ZS8T9sk7T7</recordid><startdate>2011</startdate><enddate>2011</enddate><creator>McManus, David D., MD, FACC</creator><creator>Gore, Joel, MD, FACC</creator><creator>Yarzebski, Jorge, MD, MPH</creator><creator>Spencer, Frederick, MD</creator><creator>Lessard, Darleen, MS</creator><creator>Goldberg, Robert J., PhD</creator><general>Elsevier Inc</general><general>Elsevier</general><general>Elsevier Sequoia S.A</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7TK</scope><scope>7TO</scope><scope>7TS</scope><scope>7U9</scope><scope>H94</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>2011</creationdate><title>Recent Trends in the Incidence, Treatment, and Outcomes of Patients with STEMI and NSTEMI</title><author>McManus, David D., MD, FACC ; Gore, Joel, MD, FACC ; Yarzebski, Jorge, MD, MPH ; Spencer, Frederick, MD ; Lessard, Darleen, MS ; Goldberg, Robert J., PhD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c519t-36f18f31cbee73df590d68e1511a0aeaf57ab39d096226314609eff0e1dd0e1f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Acute myocardial infarction</topic><topic>Adult</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Cardiology. Vascular system</topic><topic>Clinical outcomes</topic><topic>Coronary heart disease</topic><topic>Electrocardiography</topic><topic>Epidemiology</topic><topic>Female</topic><topic>General aspects</topic><topic>Heart</topic><topic>Heart attacks</topic><topic>Hospital Mortality</topic><topic>Hospitalization - statistics & numerical data</topic><topic>Hospitalization - trends</topic><topic>Humans</topic><topic>Incidence</topic><topic>Internal Medicine</topic><topic>Male</topic><topic>Medical prognosis</topic><topic>Medical sciences</topic><topic>Medical treatment</topic><topic>Middle Aged</topic><topic>Mortality</topic><topic>Myocardial Infarction - epidemiology</topic><topic>Myocardial Infarction - mortality</topic><topic>Myocardial Infarction - therapy</topic><topic>Public health. Hygiene</topic><topic>Public health. Hygiene-occupational medicine</topic><topic>Trends in incidence and prognosis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>McManus, David D., MD, FACC</creatorcontrib><creatorcontrib>Gore, Joel, MD, FACC</creatorcontrib><creatorcontrib>Yarzebski, Jorge, MD, MPH</creatorcontrib><creatorcontrib>Spencer, Frederick, MD</creatorcontrib><creatorcontrib>Lessard, Darleen, MS</creatorcontrib><creatorcontrib>Goldberg, Robert J., PhD</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Physical Education Index</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>McManus, David D., MD, FACC</au><au>Gore, Joel, MD, FACC</au><au>Yarzebski, Jorge, MD, MPH</au><au>Spencer, Frederick, MD</au><au>Lessard, Darleen, MS</au><au>Goldberg, Robert J., PhD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Recent Trends in the Incidence, Treatment, and Outcomes of Patients with STEMI and NSTEMI</atitle><jtitle>The American journal of medicine</jtitle><addtitle>Am J Med</addtitle><date>2011</date><risdate>2011</risdate><volume>124</volume><issue>1</issue><spage>40</spage><epage>47</epage><pages>40-47</pages><issn>0002-9343</issn><eissn>1555-7162</eissn><coden>AJMEAZ</coden><abstract>Abstract Background Despite the widespread use of electrocardiographic changes to characterize patients presenting with acute myocardial infarction, little is known about recent trends in the incidence rates, treatment, and outcomes of patients admitted for acute myocardial infarction further classified according to the presence of ST-segment elevation. The objectives of this population-based study were to examine recent trends in the incidence and death rates associated with the 2 major types of acute myocardial infarction in residents of a large central Massachusetts metropolitan area. Methods We reviewed the medical records of 5383 residents of the Worcester (MA) metropolitan area hospitalized for either ST-segment elevation acute myocardial infarction (STEMI) or non-ST-segment acute myocardial infarction (NSTEMI) between 1997 and 2005 at 11 greater Worcester medical centers. Results The incidence rates (per 100,000) of STEMI decreased appreciably (121 to 77), whereas the incidence rates of NSTEMI increased slightly (126 to 132) between 1997 and 2005. Although in-hospital and 30-day case-fatality rates remained stable in both groups, 1-year postdischarge death rates decreased between 1997 and 2005 for patients with STEMI and NSTEMI. Conclusions The results of this study demonstrate recent decreases in the magnitude of STEMI, slight increases in the incidence rates of NSTEMI, and decreases in long-term mortality in patients with STEMI and NSTEMI. Our findings suggest that acute myocardial infarction prevention and treatment efforts have resulted in favorable decreases in the frequency of STEMI and death rates from the major types of acute myocardial infarction.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>21187184</pmid><doi>10.1016/j.amjmed.2010.07.023</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Acute myocardial infarction Adult Aged Biological and medical sciences Cardiology. Vascular system Clinical outcomes Coronary heart disease Electrocardiography Epidemiology Female General aspects Heart Heart attacks Hospital Mortality Hospitalization - statistics & numerical data Hospitalization - trends Humans Incidence Internal Medicine Male Medical prognosis Medical sciences Medical treatment Middle Aged Mortality Myocardial Infarction - epidemiology Myocardial Infarction - mortality Myocardial Infarction - therapy Public health. Hygiene Public health. Hygiene-occupational medicine Trends in incidence and prognosis |
| title | Recent Trends in the Incidence, Treatment, and Outcomes of Patients with STEMI and NSTEMI |
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