Development of isoform-specific monoclonal antibodies against human IL-18 binding protein

Interleukin-18 binding protein (IL-18BP) is a soluble antagonist of IL-18 originally discovered while attempting to isolate a soluble receptor by using IL-18-ligand affinity column. IL-18BP has four isoforms (a, b, c, and d) in humans and two isoforms (c and d) in mice. The human isoforms IL-18BPa a...

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Veröffentlicht in:	Hybridoma (2005) 2010-12, Vol.29 (6), p.517-524
Hauptverfasser:	Lee, Siyoung, Kim, Sunjong, Bae, Suyoung, Choi, Jida, Hong, Jaewoo, Ryoo, Soyoon, Jhun, Hyunjhung, Hong, Kwangwon, Kim, Eunsom, Jo, Seunghyun, Her, Erk, Kim, Soohyun
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - biosynthesis Antibodies, Monoclonal - immunology Antibodies, Monoclonal - isolation & purification Binding proteins Blotting, Western Chemical properties Enzyme-Linked Immunosorbent Assay Female Humans Intercellular Signaling Peptides and Proteins - immunology Interleukin-18 Mice Mice, Inbred BALB C Monoclonal antibodies Physiological aspects Protein Isoforms - immunology
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