Differential effects of propofol and isoflurane on glucose utilization and insulin secretion

Volatile anesthetics, such as isoflurane, reverse glucose-induced inhibition of pancreatic adenosine triphosphate-sensitive potassium (KATP) channel activity, resulting in reduced insulin secretion and impaired glucose tolerance. No previous studies have investigated the effects of intravenous anest...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Life sciences (1973) 2011-01, Vol.88 (1-2), p.96-103
Hauptverfasser:	Tanaka, Katsuya, Kawano, Takashi, Tsutsumi, Yasuo M., Kinoshita, Michiko, Kakuta, Nami, Hirose, Kayo, Kimura, Masakazu, Oshita, Shuzo
Format:	Artikel
Sprache:	eng
Schlagworte:	adenosine adenosine triphosphate Adenosine Triphosphate - analysis anesthesia Anesthetics, Inhalation - pharmacology Anesthetics, Intravenous - pharmacology Animals Dose-Response Relationship, Drug equations glucose Glucose - metabolism glucose tolerance Glucose Tolerance Test glucose tolerance tests insulin Insulin - metabolism Insulin Secretion intravenous injection islets of Langerhans Islets of Langerhans - chemistry Islets of Langerhans - drug effects Islets of Langerhans - metabolism Islets of Langerhans - physiology Isoflurane Isoflurane - pharmacology KATP channels KATP Channels - drug effects KATP Channels - metabolism Male Membrane Potentials - drug effects Pancreatic β-cells Patch-Clamp Techniques potassium Propofol Propofol - pharmacology Rabbits Rats
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!