A new Pharmaceutical Aerosol Deposition Device on Cell Cultures (PADDOCC) to evaluate pulmonary drug absorption for metered dose dry powder formulations

Aerosol generation, deposition and transport in the PADDOCC system. Absorption studies with aerosol formulation delivered by metered dose inhalers across cell- and tissue-based in vitro models of the pulmonary epithelia are not trivial due to the complexity of the processes involved: (i) aerosol gen...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	European journal of pharmaceutics and biopharmaceutics 2011, Vol.77 (1), p.132-138
Hauptverfasser:	Hein, Stephanie, Bur, Michael, Schaefer, Ulrich F., Lehr, Claus-Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorption Administration, Inhalation Aerosol medicine Aerosols Air–liquid interface Albuterol - analysis Albuterol - pharmacokinetics Animal Use Alternatives Biological and medical sciences Biological Transport Blood-Air Barrier - metabolism Bronchodilator Agents - analysis Bronchodilator Agents - pharmacokinetics Budesonide - analysis Budesonide - pharmacokinetics Calu-3 cells Cell Culture Techniques Cell Line Drug Carriers Dry Powder Inhalers Electric Impedance General pharmacology Humans In vitro model Medical sciences Metered Dose Inhalers Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Powders Respiratory Mucosa - chemistry Respiratory Mucosa - metabolism Sedimentation Solubility
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!