EFFECTS OF LANKACIDIN GROUP (T2636) ANTIBIOTICS ON THE TUMOR GROWTH AND IMMUNE RESPONSE AGAINST SHEEP ERYTHROCYTES IN MICE

Antitumor and immunosuppressive activities of some lankacidin group (T2636) antibiotics were investigated in vivo and in vitro. Lankacidin-C, Lankacidin-C 8-propionate, and Lankacidin-C 14-propionate, given intraperitoneally, showed inhibitory effects at doses ranging from 25 to 1, 000mg/kg on the g...

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Veröffentlicht in:	GANN Japanese Journal of Cancer Research 1973/10/31, Vol.64(5), pp.481-492_1
Hauptverfasser:	OOTSU, Koichiro, MATSUMOTO, Takao
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibiotics, Antineoplastic - pharmacology Antibiotics, Antineoplastic - therapeutic use Antibody Formation - drug effects Body Weight - drug effects Erythrocytes - immunology HeLa Cells Immunosuppressive Agents Lactones - pharmacology Leukemia L1210 - pathology Lymphoma, Non-Hodgkin - drug therapy Lymphoma, Non-Hodgkin - pathology Melanoma - drug therapy Melanoma - pathology Mice Neoplasms, Experimental Sarcoma, Experimental Sheep - immunology
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