A Western Diet Increases Serotonin Availability in Rat Small Intestine

Diet-induced obesity is associated with changes in gastrointestinal function and induction of a mild inflammatory state. Serotonin (5-HT) containing enterochromaffin (EC) cells within the intestine respond to nutrients and are altered by inflammation. Thus, our aim was to characterize the uptake and...

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Veröffentlicht in:	Endocrinology (Philadelphia) 2011-01, Vol.152 (1), p.36-47
Hauptverfasser:	Bertrand, R. L, Senadheera, S, Markus, I, Liu, L, Howitt, L, Chen, H, Murphy, T. V, Sandow, S. L, Bertrand, P. P
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Availability Biological and medical sciences Blood Glucose Diet Disease Models, Animal Electrochemistry Electrochemistry - methods Fluoxetine Food availability Fundamental and applied biological sciences. Psychology Gene Expression Regulation Gene regulation Ileum Ileum - metabolism Intestinal motility Intestine Male mRNA Nutrients Obesity Obesity - metabolism Random Allocation Rats Rats, Sprague-Dawley RNA, Messenger - genetics RNA, Messenger - metabolism RNA-Binding Proteins - genetics RNA-Binding Proteins - metabolism Serotonin Serotonin - metabolism Serotonin transporter Small intestine Tryptophan Tryptophan hydroxylase Tryptophan Hydroxylase - genetics Tryptophan Hydroxylase - metabolism Vertebrates: endocrinology
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