Orexinergic system and pathophysiology of epilepsy

Neuropeptids orexins, also known as the hypocretins, are expressed in the lateral hypothalamus. Orexin-containing cells project widely throughout the brains, are crucial for the regulation of wakefulness and dysfunction of this system is associated with pathophysiology of narcolepsy-cataplexy. Orexi...

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Veröffentlicht in:	Georgian medical news 2010-11 (188), p.74-79
Hauptverfasser:	Doreulee, N, Alania, M, Vashalomidze, G, Skhirtladze, E, Kapanadze, Ts
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bicuculline - pharmacology CA1 Region, Hippocampal - drug effects CA1 Region, Hippocampal - physiopathology Disease Models, Animal Epilepsy - chemically induced Epilepsy - physiopathology Intracellular Signaling Peptides and Proteins - pharmacology Intracellular Signaling Peptides and Proteins - physiology Male Neuropeptides - pharmacology Neuropeptides - physiology Orexin Receptors Orexins Rats Receptors, G-Protein-Coupled - agonists Receptors, G-Protein-Coupled - physiology Receptors, Neuropeptide - agonists Receptors, Neuropeptide - physiology
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