Immunoglobulin on the Surface of Human Lymphocytes. The Detection of Kappa Chain V Region Determinants on B Cells and not on T Cells
Anti-Vκ region antisera and anti-Cκ,λ region antiserum were used to investigate the nature of antigen recognition units of T cells. The results did not support the hypothesis that T cells contain relatively large amounts of V regions with undetectable amounts of C regions which are buried in the mem...
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| Veröffentlicht in: | The Journal of immunology (1950) 1973-12, Vol.111 (6), p.1923-1925 |
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| Format: | Artikel |
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| container_end_page | 1925 |
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| container_issue | 6 |
| container_start_page | 1923 |
| container_title | The Journal of immunology (1950) |
| container_volume | 111 |
| creator | Grey, Howard M Colon, Sonia Solomon, Alan McLaughlin, Carla L |
| description | Anti-Vκ region antisera and anti-Cκ,λ region antiserum were used to investigate the nature of antigen recognition units of T cells. The results did not support the hypothesis that T cells contain relatively large amounts of V regions with undetectable amounts of C regions which are buried in the membrane but indicated that with specific anti-κI and anti-κIII antisera the detectable V region determinants were confined to the B cell population. |
| doi_str_mv | 10.4049/jimmunol.111.6.1923 |
| format | Article |
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The Detection of Kappa Chain V Region Determinants on B Cells and not on T Cells</atitle><jtitle>The Journal of immunology (1950)</jtitle><addtitle>J Immunol</addtitle><date>1973-12</date><risdate>1973</risdate><volume>111</volume><issue>6</issue><spage>1923</spage><epage>1925</epage><pages>1923-1925</pages><issn>0022-1767</issn><eissn>1550-6606</eissn><abstract>Anti-Vκ region antisera and anti-Cκ,λ region antiserum were used to investigate the nature of antigen recognition units of T cells. The results did not support the hypothesis that T cells contain relatively large amounts of V regions with undetectable amounts of C regions which are buried in the membrane but indicated that with specific anti-κI and anti-κIII antisera the detectable V region determinants were confined to the B cell population.</abstract><cop>United States</cop><pub>Am Assoc Immnol</pub><pmid>4127302</pmid><doi>10.4049/jimmunol.111.6.1923</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-1767 |
| ispartof | The Journal of immunology (1950), 1973-12, Vol.111 (6), p.1923-1925 |
| issn | 0022-1767 1550-6606 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_82093629 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Animals Antibody Specificity Autoradiography B-Lymphocytes - immunology Bence Jones Protein Cell Membrane - immunology Epitopes Humans Immune Sera Immunoglobulin Fragments - analysis Iodine Radioisotopes Rabbits - immunology T-Lymphocytes - immunology Thoracic Duct - cytology Thymus Gland - cytology |
| title | Immunoglobulin on the Surface of Human Lymphocytes. The Detection of Kappa Chain V Region Determinants on B Cells and not on T Cells |
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