Acute Circulatory Collapse of the Adrenalectomized Dog Following Plasma Infusion
Adrenalectomized dogs maintained on desoxyeorticosterone acetate developed a fatal circulatory collapse when given normal dog plasma. They showed general restlessness, a rapid fall in blood pressure and cardiac index, a decline in central venous pressure and general prostration. Most dogs developed...
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| Veröffentlicht in: | Circulation research 1958-05, Vol.6 (3), p.294-300 |
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| container_end_page | 300 |
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| container_title | Circulation research |
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| creator | Baker, Carleton H Remington, John W |
| description | Adrenalectomized dogs maintained on desoxyeorticosterone acetate developed a fatal circulatory collapse when given normal dog plasma. They showed general restlessness, a rapid fall in blood pressure and cardiac index, a decline in central venous pressure and general prostration. Most dogs developed a bloody diarrhea and a minority showed edematous swelling of the face with itching. Animals with intact spleens exhibited marked hemoconcentration, splenectomized animals did not. Blood and plasma specific gravity determinations offered no evidence for gross plasma loss. Diphenhydramine prevented the collapse. |
| doi_str_mv | 10.1161/01.RES.6.3.294 |
| format | Article |
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They showed general restlessness, a rapid fall in blood pressure and cardiac index, a decline in central venous pressure and general prostration. Most dogs developed a bloody diarrhea and a minority showed edematous swelling of the face with itching. Animals with intact spleens exhibited marked hemoconcentration, splenectomized animals did not. Blood and plasma specific gravity determinations offered no evidence for gross plasma loss. Diphenhydramine prevented the collapse.</description><identifier>ISSN: 0009-7330</identifier><identifier>EISSN: 1524-4571</identifier><identifier>DOI: 10.1161/01.RES.6.3.294</identifier><identifier>PMID: 13523810</identifier><language>eng</language><publisher>United States: American Heart Association, Inc</publisher><subject>Adrenalectomy ; Animals ; Dogs ; Old Medline ; Plasma ; Shock</subject><ispartof>Circulation research, 1958-05, Vol.6 (3), p.294-300</ispartof><rights>1958 American Heart Association, Inc.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4132-fed341380c90ee897d8514906b64fa8bdf93209f8b385c24eb82de22711c383e3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,3674,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/13523810$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Baker, Carleton H</creatorcontrib><creatorcontrib>Remington, John W</creatorcontrib><title>Acute Circulatory Collapse of the Adrenalectomized Dog Following Plasma Infusion</title><title>Circulation research</title><addtitle>Circ Res</addtitle><description>Adrenalectomized dogs maintained on desoxyeorticosterone acetate developed a fatal circulatory collapse when given normal dog plasma. They showed general restlessness, a rapid fall in blood pressure and cardiac index, a decline in central venous pressure and general prostration. Most dogs developed a bloody diarrhea and a minority showed edematous swelling of the face with itching. Animals with intact spleens exhibited marked hemoconcentration, splenectomized animals did not. Blood and plasma specific gravity determinations offered no evidence for gross plasma loss. 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| fulltext | fulltext |
| identifier | ISSN: 0009-7330 |
| ispartof | Circulation research, 1958-05, Vol.6 (3), p.294-300 |
| issn | 0009-7330 1524-4571 |
| language | eng |
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| source | MEDLINE; American Heart Association Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Journals@Ovid Complete |
| subjects | Adrenalectomy Animals Dogs Old Medline Plasma Shock |
| title | Acute Circulatory Collapse of the Adrenalectomized Dog Following Plasma Infusion |
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