Role of PET/CT in congenital histiocytosis
Congenital Langerhans cell histiocytosis (LCH) is a rare, but often severe, form of LCH. Although a more benign single-system congenital LCH has been described, most cases present as multisystem disease with poorer prognosis and are often treated with systemic chemotherapy. Imaging plays a central r...
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| Veröffentlicht in: | Pediatric radiology 2010-12, Vol.40 (Suppl 1), p.57-61 |
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| container_issue | Suppl 1 |
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| container_title | Pediatric radiology |
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| creator | Udayasankar, Unni K. Alazraki, Adina L. Simoneaux, Stephen F. |
| description | Congenital Langerhans cell histiocytosis (LCH) is a rare, but often severe, form of LCH. Although a more benign single-system congenital LCH has been described, most cases present as multisystem disease with poorer prognosis and are often treated with systemic chemotherapy. Imaging plays a central role in diagnosis, initial staging and assessment of treatment response. PET/CT is increasingly utilized for pediatric LCH. We report a unique case with PET/CT used as an imaging tool in staging and evaluating treatment response in congenital multisystem LCH. |
| doi_str_mv | 10.1007/s00247-010-1765-9 |
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Although a more benign single-system congenital LCH has been described, most cases present as multisystem disease with poorer prognosis and are often treated with systemic chemotherapy. Imaging plays a central role in diagnosis, initial staging and assessment of treatment response. PET/CT is increasingly utilized for pediatric LCH. 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Although a more benign single-system congenital LCH has been described, most cases present as multisystem disease with poorer prognosis and are often treated with systemic chemotherapy. Imaging plays a central role in diagnosis, initial staging and assessment of treatment response. PET/CT is increasingly utilized for pediatric LCH. We report a unique case with PET/CT used as an imaging tool in staging and evaluating treatment response in congenital multisystem LCH.</description><subject>Case Report</subject><subject>Drug therapy</subject><subject>Histiocytosis, Langerhans-Cell - congenital</subject><subject>Histiocytosis, Langerhans-Cell - diagnosis</subject><subject>Humans</subject><subject>Imaging</subject><subject>Infant, Newborn</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Neuroradiology</subject><subject>Nuclear Medicine</subject><subject>Oncology</subject><subject>Pediatrics</subject><subject>Positron-Emission Tomography</subject><subject>Radiology</subject><subject>Subtraction Technique</subject><subject>Tomography, X-Ray Computed</subject><subject>Ultrasound</subject><subject>Whole Body Imaging</subject><issn>0301-0449</issn><issn>1432-1998</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp1kN9LwzAQx4Mobk7_AF-k4IMgxN1dsrZ5lDF_wECR-RzaLtGOrplN-7D_3sxOEcGncLnPfe_4MHaOcIMAydgDkEw4IHBM4glXB2yIUhBHpdJDNgQByEFKNWAn3q8AQExQHLMBQUyCknjIrl9cZSJno-fZYjxdRGUdFa5-M3XZZlX0Xvq2dMW2db70p-zIZpU3Z_t3xF7vZovpA58_3T9Ob-e8EAm2XJJVkMo4l8YYymVsl0sqFEBqBaivP0CZhcOlISmUQSKYTCwolVu0qRixqz5307iPzvhWr0tfmKrKauM6r1OCRIlYUiAv_5Ar1zV1OE4jIklEqXZ52FNF47xvjNWbplxnzVYj6J1H3XvUsKuDR63CzMU-ucvXZvkz8S0uANQDPrSCr-bX6n9TPwFg-3oG</recordid><startdate>20101201</startdate><enddate>20101201</enddate><creator>Udayasankar, Unni K.</creator><creator>Alazraki, Adina L.</creator><creator>Simoneaux, Stephen F.</creator><general>Springer-Verlag</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7RV</scope><scope>7TK</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20101201</creationdate><title>Role of PET/CT in congenital histiocytosis</title><author>Udayasankar, Unni K. ; 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| subjects | Case Report Drug therapy Histiocytosis, Langerhans-Cell - congenital Histiocytosis, Langerhans-Cell - diagnosis Humans Imaging Infant, Newborn Male Medicine Medicine & Public Health Neuroradiology Nuclear Medicine Oncology Pediatrics Positron-Emission Tomography Radiology Subtraction Technique Tomography, X-Ray Computed Ultrasound Whole Body Imaging |
| title | Role of PET/CT in congenital histiocytosis |
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