CCR10 and CCL27 are overexpressed in cutaneous squamous cell carcinoma

C–C chemokine receptor (CCR)10 is a specific receptor for chemokine ligand (CCL)27, a selective chemoattractant for skin-associated memory T cells to cutaneous sites. In melanoma, CCR10 increases the ability of neoplastic cells to grow, invade tissues, disseminate to lymph nodes, and escape the host...

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Veröffentlicht in:	Pathology, research and practice research and practice, 2011-01, Vol.207 (1), p.43-48
Hauptverfasser:	Kai, Hiromichi, Kadono, Takafumi, Kakinuma, Takashi, Tomita, Manabu, Ohmatsu, Hanako, Asano, Yoshihide, Tada, Yayoi, Sugaya, Makoto, Sato, Shinichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Biopsy Bowen's Disease - immunology Bowen's Disease - metabolism Bowen's Disease - pathology Carcinoma, Basal Cell - immunology Carcinoma, Basal Cell - metabolism Carcinoma, Basal Cell - pathology Carcinoma, Squamous Cell - immunology Carcinoma, Squamous Cell - metabolism Carcinoma, Squamous Cell - pathology CCL27 CCR10 Cell Line, Tumor Chemokine CCL27 - metabolism Gene Expression Regulation, Neoplastic Humans Immunohistochemistry Interleukin-1beta - immunology Interleukin-1beta - metabolism Keratosis, Actinic - immunology Keratosis, Actinic - metabolism Keratosis, Actinic - pathology Keratosis, Seborrheic - immunology Keratosis, Seborrheic - metabolism Keratosis, Seborrheic - pathology Receptors, CCR10 - metabolism Skin - metabolism Skin - pathology Skin Neoplasms - immunology Skin Neoplasms - metabolism Skin Neoplasms - pathology Squamous cell carcinoma Tumor Necrosis Factor-alpha - immunology Tumor Necrosis Factor-alpha - metabolism
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