Reliability assessment and validation of the Melasma Area and Severity Index (MASI) and a new modified MASI scoring method
Background The Melasma Area and Severity Index (MASI), the most commonly used outcome measure for melasma, has not been validated. Objective We sought to determine the reliability and validity of the MASI. Methods After standardized training, 6 raters independently rated 21 patients with mild to sev...
Gespeichert in:
| Veröffentlicht in: | Journal of the American Academy of Dermatology 2011-01, Vol.64 (1), p.78-83.e2 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 83.e2 |
|---|---|
| container_issue | 1 |
| container_start_page | 78 |
| container_title | Journal of the American Academy of Dermatology |
| container_volume | 64 |
| creator | Pandya, Amit G., MD Hynan, Linda S., PhD Bhore, Rafia, PhD Riley, Fransell Copeland, MS Guevara, Ian L., MD Grimes, Pearl, MD Nordlund, James J., MD Rendon, Marta, MD Taylor, Susan, MD Gottschalk, Ronald W., MD, FRCPC Agim, Nnenna G., MD Ortonne, Jean-Paul, MD |
| description | Background The Melasma Area and Severity Index (MASI), the most commonly used outcome measure for melasma, has not been validated. Objective We sought to determine the reliability and validity of the MASI. Methods After standardized training, 6 raters independently rated 21 patients with mild to severe melasma once daily over a period of 2 days to determine intrarater and interrater reliability. Validation was performed by comparing the MASI with the melasma severity scale. The darkness component of the MASI was validated by comparing it with the difference between mexameter scores for affected versus adjacent normal-appearing skin. The area component of the MASI was validated by comparing it with the area of each section of the face determined by computer-based measurement software. Results The MASI score showed good reliability within and between raters and was found to be valid when compared with the melasma severity scale, mexameter scores, and area measurements. Homogeneity assessment by raters showed the least agreement and can be removed from the MASI score without any loss of reliability. Limitations Patients were limited to Hispanic, African, and Asian backgrounds. Conclusion The MASI is a reliable measure of melasma severity. Area of involvement and darkness are sufficient for accurate measurement of the severity of melasma and homogeneity can be eliminated. |
| doi_str_mv | 10.1016/j.jaad.2009.10.051 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_820790061</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>1_s2_0_S0190962209023020</els_id><sourcerecordid>820790061</sourcerecordid><originalsourceid>FETCH-LOGICAL-c484t-d1f93f81c35e165780474b1ec5465381928958fbfe44e8a6568974f81cd4c393</originalsourceid><addsrcrecordid>eNp9kk2LFDEQhoMo7rj6BzxILqIeeqz0RzoBEYbFj4FdBGfvIZNUu2m7kzXpGR1_vemdUcGDp0DV81aKhyLkKYMlA8Zf98tea7ssAWQuLKFh98iCgWwL3or2PlkAk1BIXpZn5FFKPWSwrtqH5KyESgrJYUF-fsbB6a0b3HSgOiVMaUQ_Ue0t3evBWT254Gno6HSD9AoHnUZNVxH1HbLBPcY5uvYWf9CXV6vN-tVdR1OP3-kYrOscWjo3aDIhOv-FjjjdBPuYPOj0kPDJ6T0n1-_fXV98LC4_fVhfrC4LU4t6KizrZNUJZqoGGW9aAXVbbxmapuZNJZgshWxEt-2wrlFo3nAh23oO2NpUsjonL45jb2P4tsM0qdElg8OgPYZdUqKEVgJwlsnySJoYUorYqdvoRh0PioGajatezcbVbHyuZeM59Ow0frcd0f6J_FacgecnQCejhy5qb1z6y1WCN1A1mXtz5DC72DuMKhmH3qB1Ec2kbHD_3-PtP3EzOO_yj1_xgKkPu-izZcVUKhWozXwb82mAhLKCvO0vJQ-yCw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>820790061</pqid></control><display><type>article</type><title>Reliability assessment and validation of the Melasma Area and Severity Index (MASI) and a new modified MASI scoring method</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Pandya, Amit G., MD ; Hynan, Linda S., PhD ; Bhore, Rafia, PhD ; Riley, Fransell Copeland, MS ; Guevara, Ian L., MD ; Grimes, Pearl, MD ; Nordlund, James J., MD ; Rendon, Marta, MD ; Taylor, Susan, MD ; Gottschalk, Ronald W., MD, FRCPC ; Agim, Nnenna G., MD ; Ortonne, Jean-Paul, MD</creator><creatorcontrib>Pandya, Amit G., MD ; Hynan, Linda S., PhD ; Bhore, Rafia, PhD ; Riley, Fransell Copeland, MS ; Guevara, Ian L., MD ; Grimes, Pearl, MD ; Nordlund, James J., MD ; Rendon, Marta, MD ; Taylor, Susan, MD ; Gottschalk, Ronald W., MD, FRCPC ; Agim, Nnenna G., MD ; Ortonne, Jean-Paul, MD</creatorcontrib><description>Background The Melasma Area and Severity Index (MASI), the most commonly used outcome measure for melasma, has not been validated. Objective We sought to determine the reliability and validity of the MASI. Methods After standardized training, 6 raters independently rated 21 patients with mild to severe melasma once daily over a period of 2 days to determine intrarater and interrater reliability. Validation was performed by comparing the MASI with the melasma severity scale. The darkness component of the MASI was validated by comparing it with the difference between mexameter scores for affected versus adjacent normal-appearing skin. The area component of the MASI was validated by comparing it with the area of each section of the face determined by computer-based measurement software. Results The MASI score showed good reliability within and between raters and was found to be valid when compared with the melasma severity scale, mexameter scores, and area measurements. Homogeneity assessment by raters showed the least agreement and can be removed from the MASI score without any loss of reliability. Limitations Patients were limited to Hispanic, African, and Asian backgrounds. Conclusion The MASI is a reliable measure of melasma severity. Area of involvement and darkness are sufficient for accurate measurement of the severity of melasma and homogeneity can be eliminated.</description><identifier>ISSN: 0190-9622</identifier><identifier>EISSN: 1097-6787</identifier><identifier>DOI: 10.1016/j.jaad.2009.10.051</identifier><identifier>PMID: 20398960</identifier><identifier>CODEN: JAADDB</identifier><language>eng</language><publisher>New York, NY: Mosby, Inc</publisher><subject>Adult ; African Americans - statistics & numerical data ; Age Factors ; Analysis of Variance ; Asian Continental Ancestry Group - statistics & numerical data ; Biological and medical sciences ; clinical trials ; Cohort Studies ; Confidence Intervals ; Dermatology ; evidence-based medicine ; Female ; Forecasting ; Hispanic Americans - statistics & numerical data ; Humans ; Male ; Medical sciences ; Melanosis - diagnosis ; Melanosis - ethnology ; melasma ; Middle Aged ; Observer Variation ; outcome measure ; Pigmentary diseases of the skin ; pigmentation ; Reproducibility of Results ; Research Design - trends ; Risk Assessment ; Severity of Illness Index ; Sex Factors ; United States ; validation ; Young Adult</subject><ispartof>Journal of the American Academy of Dermatology, 2011-01, Vol.64 (1), p.78-83.e2</ispartof><rights>American Academy of Dermatology, Inc.</rights><rights>2009 American Academy of Dermatology, Inc.</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2009 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c484t-d1f93f81c35e165780474b1ec5465381928958fbfe44e8a6568974f81cd4c393</citedby><cites>FETCH-LOGICAL-c484t-d1f93f81c35e165780474b1ec5465381928958fbfe44e8a6568974f81cd4c393</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0190962209023020$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=23865035$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20398960$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pandya, Amit G., MD</creatorcontrib><creatorcontrib>Hynan, Linda S., PhD</creatorcontrib><creatorcontrib>Bhore, Rafia, PhD</creatorcontrib><creatorcontrib>Riley, Fransell Copeland, MS</creatorcontrib><creatorcontrib>Guevara, Ian L., MD</creatorcontrib><creatorcontrib>Grimes, Pearl, MD</creatorcontrib><creatorcontrib>Nordlund, James J., MD</creatorcontrib><creatorcontrib>Rendon, Marta, MD</creatorcontrib><creatorcontrib>Taylor, Susan, MD</creatorcontrib><creatorcontrib>Gottschalk, Ronald W., MD, FRCPC</creatorcontrib><creatorcontrib>Agim, Nnenna G., MD</creatorcontrib><creatorcontrib>Ortonne, Jean-Paul, MD</creatorcontrib><title>Reliability assessment and validation of the Melasma Area and Severity Index (MASI) and a new modified MASI scoring method</title><title>Journal of the American Academy of Dermatology</title><addtitle>J Am Acad Dermatol</addtitle><description>Background The Melasma Area and Severity Index (MASI), the most commonly used outcome measure for melasma, has not been validated. Objective We sought to determine the reliability and validity of the MASI. Methods After standardized training, 6 raters independently rated 21 patients with mild to severe melasma once daily over a period of 2 days to determine intrarater and interrater reliability. Validation was performed by comparing the MASI with the melasma severity scale. The darkness component of the MASI was validated by comparing it with the difference between mexameter scores for affected versus adjacent normal-appearing skin. The area component of the MASI was validated by comparing it with the area of each section of the face determined by computer-based measurement software. Results The MASI score showed good reliability within and between raters and was found to be valid when compared with the melasma severity scale, mexameter scores, and area measurements. Homogeneity assessment by raters showed the least agreement and can be removed from the MASI score without any loss of reliability. Limitations Patients were limited to Hispanic, African, and Asian backgrounds. Conclusion The MASI is a reliable measure of melasma severity. Area of involvement and darkness are sufficient for accurate measurement of the severity of melasma and homogeneity can be eliminated.</description><subject>Adult</subject><subject>African Americans - statistics & numerical data</subject><subject>Age Factors</subject><subject>Analysis of Variance</subject><subject>Asian Continental Ancestry Group - statistics & numerical data</subject><subject>Biological and medical sciences</subject><subject>clinical trials</subject><subject>Cohort Studies</subject><subject>Confidence Intervals</subject><subject>Dermatology</subject><subject>evidence-based medicine</subject><subject>Female</subject><subject>Forecasting</subject><subject>Hispanic Americans - statistics & numerical data</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Melanosis - diagnosis</subject><subject>Melanosis - ethnology</subject><subject>melasma</subject><subject>Middle Aged</subject><subject>Observer Variation</subject><subject>outcome measure</subject><subject>Pigmentary diseases of the skin</subject><subject>pigmentation</subject><subject>Reproducibility of Results</subject><subject>Research Design - trends</subject><subject>Risk Assessment</subject><subject>Severity of Illness Index</subject><subject>Sex Factors</subject><subject>United States</subject><subject>validation</subject><subject>Young Adult</subject><issn>0190-9622</issn><issn>1097-6787</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kk2LFDEQhoMo7rj6BzxILqIeeqz0RzoBEYbFj4FdBGfvIZNUu2m7kzXpGR1_vemdUcGDp0DV81aKhyLkKYMlA8Zf98tea7ssAWQuLKFh98iCgWwL3or2PlkAk1BIXpZn5FFKPWSwrtqH5KyESgrJYUF-fsbB6a0b3HSgOiVMaUQ_Ue0t3evBWT254Gno6HSD9AoHnUZNVxH1HbLBPcY5uvYWf9CXV6vN-tVdR1OP3-kYrOscWjo3aDIhOv-FjjjdBPuYPOj0kPDJ6T0n1-_fXV98LC4_fVhfrC4LU4t6KizrZNUJZqoGGW9aAXVbbxmapuZNJZgshWxEt-2wrlFo3nAh23oO2NpUsjonL45jb2P4tsM0qdElg8OgPYZdUqKEVgJwlsnySJoYUorYqdvoRh0PioGajatezcbVbHyuZeM59Ow0frcd0f6J_FacgecnQCejhy5qb1z6y1WCN1A1mXtz5DC72DuMKhmH3qB1Ec2kbHD_3-PtP3EzOO_yj1_xgKkPu-izZcVUKhWozXwb82mAhLKCvO0vJQ-yCw</recordid><startdate>20110101</startdate><enddate>20110101</enddate><creator>Pandya, Amit G., MD</creator><creator>Hynan, Linda S., PhD</creator><creator>Bhore, Rafia, PhD</creator><creator>Riley, Fransell Copeland, MS</creator><creator>Guevara, Ian L., MD</creator><creator>Grimes, Pearl, MD</creator><creator>Nordlund, James J., MD</creator><creator>Rendon, Marta, MD</creator><creator>Taylor, Susan, MD</creator><creator>Gottschalk, Ronald W., MD, FRCPC</creator><creator>Agim, Nnenna G., MD</creator><creator>Ortonne, Jean-Paul, MD</creator><general>Mosby, Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20110101</creationdate><title>Reliability assessment and validation of the Melasma Area and Severity Index (MASI) and a new modified MASI scoring method</title><author>Pandya, Amit G., MD ; Hynan, Linda S., PhD ; Bhore, Rafia, PhD ; Riley, Fransell Copeland, MS ; Guevara, Ian L., MD ; Grimes, Pearl, MD ; Nordlund, James J., MD ; Rendon, Marta, MD ; Taylor, Susan, MD ; Gottschalk, Ronald W., MD, FRCPC ; Agim, Nnenna G., MD ; Ortonne, Jean-Paul, MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c484t-d1f93f81c35e165780474b1ec5465381928958fbfe44e8a6568974f81cd4c393</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Adult</topic><topic>African Americans - statistics & numerical data</topic><topic>Age Factors</topic><topic>Analysis of Variance</topic><topic>Asian Continental Ancestry Group - statistics & numerical data</topic><topic>Biological and medical sciences</topic><topic>clinical trials</topic><topic>Cohort Studies</topic><topic>Confidence Intervals</topic><topic>Dermatology</topic><topic>evidence-based medicine</topic><topic>Female</topic><topic>Forecasting</topic><topic>Hispanic Americans - statistics & numerical data</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Melanosis - diagnosis</topic><topic>Melanosis - ethnology</topic><topic>melasma</topic><topic>Middle Aged</topic><topic>Observer Variation</topic><topic>outcome measure</topic><topic>Pigmentary diseases of the skin</topic><topic>pigmentation</topic><topic>Reproducibility of Results</topic><topic>Research Design - trends</topic><topic>Risk Assessment</topic><topic>Severity of Illness Index</topic><topic>Sex Factors</topic><topic>United States</topic><topic>validation</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pandya, Amit G., MD</creatorcontrib><creatorcontrib>Hynan, Linda S., PhD</creatorcontrib><creatorcontrib>Bhore, Rafia, PhD</creatorcontrib><creatorcontrib>Riley, Fransell Copeland, MS</creatorcontrib><creatorcontrib>Guevara, Ian L., MD</creatorcontrib><creatorcontrib>Grimes, Pearl, MD</creatorcontrib><creatorcontrib>Nordlund, James J., MD</creatorcontrib><creatorcontrib>Rendon, Marta, MD</creatorcontrib><creatorcontrib>Taylor, Susan, MD</creatorcontrib><creatorcontrib>Gottschalk, Ronald W., MD, FRCPC</creatorcontrib><creatorcontrib>Agim, Nnenna G., MD</creatorcontrib><creatorcontrib>Ortonne, Jean-Paul, MD</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the American Academy of Dermatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pandya, Amit G., MD</au><au>Hynan, Linda S., PhD</au><au>Bhore, Rafia, PhD</au><au>Riley, Fransell Copeland, MS</au><au>Guevara, Ian L., MD</au><au>Grimes, Pearl, MD</au><au>Nordlund, James J., MD</au><au>Rendon, Marta, MD</au><au>Taylor, Susan, MD</au><au>Gottschalk, Ronald W., MD, FRCPC</au><au>Agim, Nnenna G., MD</au><au>Ortonne, Jean-Paul, MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Reliability assessment and validation of the Melasma Area and Severity Index (MASI) and a new modified MASI scoring method</atitle><jtitle>Journal of the American Academy of Dermatology</jtitle><addtitle>J Am Acad Dermatol</addtitle><date>2011-01-01</date><risdate>2011</risdate><volume>64</volume><issue>1</issue><spage>78</spage><epage>83.e2</epage><pages>78-83.e2</pages><issn>0190-9622</issn><eissn>1097-6787</eissn><coden>JAADDB</coden><abstract>Background The Melasma Area and Severity Index (MASI), the most commonly used outcome measure for melasma, has not been validated. Objective We sought to determine the reliability and validity of the MASI. Methods After standardized training, 6 raters independently rated 21 patients with mild to severe melasma once daily over a period of 2 days to determine intrarater and interrater reliability. Validation was performed by comparing the MASI with the melasma severity scale. The darkness component of the MASI was validated by comparing it with the difference between mexameter scores for affected versus adjacent normal-appearing skin. The area component of the MASI was validated by comparing it with the area of each section of the face determined by computer-based measurement software. Results The MASI score showed good reliability within and between raters and was found to be valid when compared with the melasma severity scale, mexameter scores, and area measurements. Homogeneity assessment by raters showed the least agreement and can be removed from the MASI score without any loss of reliability. Limitations Patients were limited to Hispanic, African, and Asian backgrounds. Conclusion The MASI is a reliable measure of melasma severity. Area of involvement and darkness are sufficient for accurate measurement of the severity of melasma and homogeneity can be eliminated.</abstract><cop>New York, NY</cop><pub>Mosby, Inc</pub><pmid>20398960</pmid><doi>10.1016/j.jaad.2009.10.051</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0190-9622 |
| ispartof | Journal of the American Academy of Dermatology, 2011-01, Vol.64 (1), p.78-83.e2 |
| issn | 0190-9622 1097-6787 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_820790061 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adult African Americans - statistics & numerical data Age Factors Analysis of Variance Asian Continental Ancestry Group - statistics & numerical data Biological and medical sciences clinical trials Cohort Studies Confidence Intervals Dermatology evidence-based medicine Female Forecasting Hispanic Americans - statistics & numerical data Humans Male Medical sciences Melanosis - diagnosis Melanosis - ethnology melasma Middle Aged Observer Variation outcome measure Pigmentary diseases of the skin pigmentation Reproducibility of Results Research Design - trends Risk Assessment Severity of Illness Index Sex Factors United States validation Young Adult |
| title | Reliability assessment and validation of the Melasma Area and Severity Index (MASI) and a new modified MASI scoring method |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-02T04%3A54%3A00IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Reliability%20assessment%20and%20validation%20of%20the%20Melasma%20Area%20and%20Severity%20Index%20(MASI)%20and%20a%20new%20modified%20MASI%20scoring%20method&rft.jtitle=Journal%20of%20the%20American%20Academy%20of%20Dermatology&rft.au=Pandya,%20Amit%20G.,%20MD&rft.date=2011-01-01&rft.volume=64&rft.issue=1&rft.spage=78&rft.epage=83.e2&rft.pages=78-83.e2&rft.issn=0190-9622&rft.eissn=1097-6787&rft.coden=JAADDB&rft_id=info:doi/10.1016/j.jaad.2009.10.051&rft_dat=%3Cproquest_cross%3E820790061%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=820790061&rft_id=info:pmid/20398960&rft_els_id=1_s2_0_S0190962209023020&rfr_iscdi=true |