Anti-Müllerian hormone serum levels predict response to controlled ovarian hyperstimulation but not embryo quality or pregnancy outcome in oocyte donation

The objective of this retrospective cross-sectional study was to evaluate the value of basal serum anti-Müllerian hormone (AMH) levels as a predictor of ovarian response and pregnancy outcome in a donor egg program. The study showed that AMH was superior to other biomarkers of ovarian reserve in pre...

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Veröffentlicht in:Fertility and sterility 2011, Vol.95 (1), p.410-412
Hauptverfasser: Riggs, Ryan, M.D, Kimble, Thomas, M.D, Oehninger, Sergio, M.D., Ph.D, Bocca, Silvina, M.D., Ph.D, Zhao, Yueqin, Ph.D, Leader, Ben, M.D., Ph.D, Stadtmauer, Laurel, M.D., Ph.D
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container_end_page 412
container_issue 1
container_start_page 410
container_title Fertility and sterility
container_volume 95
creator Riggs, Ryan, M.D
Kimble, Thomas, M.D
Oehninger, Sergio, M.D., Ph.D
Bocca, Silvina, M.D., Ph.D
Zhao, Yueqin, Ph.D
Leader, Ben, M.D., Ph.D
Stadtmauer, Laurel, M.D., Ph.D
description The objective of this retrospective cross-sectional study was to evaluate the value of basal serum anti-Müllerian hormone (AMH) levels as a predictor of ovarian response and pregnancy outcome in a donor egg program. The study showed that AMH was superior to other biomarkers of ovarian reserve in predicting low and high response in young women selected as oocyte donors, but that it was not predictive of embryo morphology or pregnancy outcome in the recipient population.
doi_str_mv 10.1016/j.fertnstert.2010.07.1042
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source MEDLINE; ScienceDirect Journals (5 years ago - present); EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection
subjects Adult
animal ovaries
Anti-Mullerian Hormone - blood
Anti-Müllerian hormone
Biological and medical sciences
biomarkers
Biomarkers - blood
Blastocyst
blood serum
cross-sectional studies
eggs
Embryo Transfer
Female
FSH
Gynecology. Andrology. Obstetrics
Humans
inhibin B
Internal Medicine
Medical sciences
Obstetrics and Gynecology
Oocyte Donation
oocytes
Oocytes - cytology
ovarian reserve
Ovulation Induction - methods
prediction
Predictive Value of Tests
Pregnancy
Pregnancy Outcome
ROC Curve
women
title Anti-Müllerian hormone serum levels predict response to controlled ovarian hyperstimulation but not embryo quality or pregnancy outcome in oocyte donation
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