Efficacy and safety of metformin for treatment of type 2 diabetes in elderly Japanese patients

Aim: The maximum dosage of metformin allowed for clinical use in Japan is much less than half that in Western countries, making it difficult to apply the results of clinical trials in Western countries to Japanese patients. In particular, the efficacy and safety of metformin in elderly patients are...

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Veröffentlicht in:	Geriatrics & gerontology international 2011-01, Vol.11 (1), p.55-62
Hauptverfasser:	Ito, Hiroyuki, Ohno, Yasuhiro, Yamauchi, Takaaki, Kawabata, Yumiko, Ikegami, Hiroshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Age Distribution Age Factors Aged Aged, 80 and over biguanide Diabetes Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - drug therapy Diabetes Mellitus, Type 2 - epidemiology Dose-Response Relationship, Drug Drug therapy Female Follow-Up Studies Glycated Hemoglobin A - drug effects Glycated Hemoglobin A - metabolism Humans Hypoglycemic Agents - administration & dosage Hypoglycemic Agents - therapeutic use insulin resistance Japan - epidemiology lactic acidosis Male metformin Metformin - administration & dosage Metformin - therapeutic use Middle Aged Older people Prevalence Retrospective Studies Treatment Outcome type 2 diabetes Young Adult
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