Interrelationship of drugs influencing arterial pressure in man

Comparison of hemodynamic changes (cardiac output, renal plasma flow, and extremity blood flow) observed during reserpine-induced hypotension with those occurring during pentolinium-induced hypotension suggests better adaptation following reserpine. This difference is believed to be related to the g...

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Veröffentlicht in:Circulation (New York, N.Y.) N.Y.), 1958-02, Vol.17 (2), p.208-212
Hauptverfasser: REDISCH, W, TANGCO, F F, LEWIS, A J, ANTONIO, M A, DECRINIS, K, STEELE, J M
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container_end_page 212
container_issue 2
container_start_page 208
container_title Circulation (New York, N.Y.)
container_volume 17
creator REDISCH, W
TANGCO, F F
LEWIS, A J
ANTONIO, M A
DECRINIS, K
STEELE, J M
description Comparison of hemodynamic changes (cardiac output, renal plasma flow, and extremity blood flow) observed during reserpine-induced hypotension with those occurring during pentolinium-induced hypotension suggests better adaptation following reserpine. This difference is believed to be related to the gradation of onset of hypotension. It was found that reserpine-induced hypotension is potentiated by norepinephrine, and pentolinium-induced hypotension by serotonin. Pretreatment with the hypotensive agent increased the pressor response to norepinephrine and serotonin respectively, if the pressor substance was administered before the onset of hypotension.
doi_str_mv 10.1161/01.CIR.17.2.208
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source MEDLINE; American Heart Association Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Journals@Ovid Ovid Autoload
subjects Blood Pressure - drug effects
Blood Pressure Determination
Cardiovascular Agents
Muscle Relaxants, Central - pharmacology
Norepinephrine - pharmacology
Old Medline
Reserpine - pharmacology
Serotonin
Serotonin Agents
title Interrelationship of drugs influencing arterial pressure in man
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