Comparison of bovine corneal and scleral mucopolysaccharides

The mucopolysaccharide components of bovine cornea and sclera were investigated, and the data obtained for the cornea confirm the results reported in the literature. Two fractions were isolated from the sclera, each amounting to about one half of the total mucopolysaccharide content: chondroitin sulfate B, and an inconclusively resolved mixture probably containing chondroitin sulfates A and C. No keratosulfate and only trace amounts of hyaluronic acid were found in the sclera. The sclera appears to be the only connective tissue investigated so far which does not contain any appreciable amounts of non-sulfated mucopolysaccharides.