Phenols as Inhibitors of the Heparin Co-factor of Plasma
PHENOLS counteract the antithrombic activity of plasma and serum 1 . The antithrombic activity is present in a protein fraction which also contains the co-factor required for the anticoagulant effect of heparin 2 . The antithrombic and the heparin co-factor activity are present in the α-globulin fra...
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| Veröffentlicht in: | Nature (London) 1957-11, Vol.180 (4593), p.990-990 |
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| container_title | Nature (London) |
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| creator | FANTL, P MARR, A. G. M |
| description | PHENOLS counteract the antithrombic activity of plasma and serum
1
. The antithrombic activity is present in a protein fraction which also contains the co-factor required for the anticoagulant effect of heparin
2
. The antithrombic and the heparin co-factor activity are present in the α-globulin fraction of human plasma
3
. It was therefore of interest to test the influence of phenols on heparin activity in plasma. |
| doi_str_mv | 10.1038/180990a0 |
| format | Article |
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1
. The antithrombic activity is present in a protein fraction which also contains the co-factor required for the anticoagulant effect of heparin
2
. The antithrombic and the heparin co-factor activity are present in the α-globulin fraction of human plasma
3
. It was therefore of interest to test the influence of phenols on heparin activity in plasma.</description><identifier>ISSN: 0028-0836</identifier><identifier>EISSN: 1476-4687</identifier><identifier>DOI: 10.1038/180990a0</identifier><identifier>PMID: 13483578</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>Heparin ; Heparin Antagonists ; Humanities and Social Sciences ; Humans ; letter ; Lipase ; multidisciplinary ; Old Medline ; Phenols - pharmacology ; Plasma ; Science ; Science (multidisciplinary)</subject><ispartof>Nature (London), 1957-11, Vol.180 (4593), p.990-990</ispartof><rights>Springer Nature Limited 1957</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c333t-c0f3a022549ecc389dd69ae7edd5b0462e6c44f43c2325c9dec88aa87f807f703</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,2727,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/13483578$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>FANTL, P</creatorcontrib><creatorcontrib>MARR, A. G. M</creatorcontrib><title>Phenols as Inhibitors of the Heparin Co-factor of Plasma</title><title>Nature (London)</title><addtitle>Nature</addtitle><addtitle>Nature</addtitle><description>PHENOLS counteract the antithrombic activity of plasma and serum
1
. The antithrombic activity is present in a protein fraction which also contains the co-factor required for the anticoagulant effect of heparin
2
. The antithrombic and the heparin co-factor activity are present in the α-globulin fraction of human plasma
3
. It was therefore of interest to test the influence of phenols on heparin activity in plasma.</description><subject>Heparin</subject><subject>Heparin Antagonists</subject><subject>Humanities and Social Sciences</subject><subject>Humans</subject><subject>letter</subject><subject>Lipase</subject><subject>multidisciplinary</subject><subject>Old Medline</subject><subject>Phenols - pharmacology</subject><subject>Plasma</subject><subject>Science</subject><subject>Science (multidisciplinary)</subject><issn>0028-0836</issn><issn>1476-4687</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1957</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kDFPwzAQRi0EoqUg8QtQJgRD4Bw78WVEFdBKlegAc-Q6Z5oqiYudDPx7UrVVN6Yb3tOT7mPslsMTB4HPHCHPQcMZG3OpslhmqM7ZGCDBGFBkI3YVwgYAUq7kJRtxIVGkCscMl2tqXR0iHaJ5u65WVed8iJyNujVFM9pqX7XR1MVWm4HswLLWodHX7MLqOtDN4U7Y19vr53QWLz7e59OXRWyEEF1swAoNSZLKnIwRmJdllmtSVJbpCmSWUGaktFKYRCSpyUsyiFqjsgjKKhATdr_vbr376Sl0RVMFQ3WtW3J9KDABrvIMB_FhLxrvQvBki62vGu1_Cw7FbqXiuNKg3h2a_aqh8iQeZhmEx70QBtR-ky82rvft8Oc_sVZ3vadT7Cj8AaSad5Q</recordid><startdate>19571109</startdate><enddate>19571109</enddate><creator>FANTL, P</creator><creator>MARR, A. G. M</creator><general>Nature Publishing Group UK</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19571109</creationdate><title>Phenols as Inhibitors of the Heparin Co-factor of Plasma</title><author>FANTL, P ; MARR, A. G. M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c333t-c0f3a022549ecc389dd69ae7edd5b0462e6c44f43c2325c9dec88aa87f807f703</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1957</creationdate><topic>Heparin</topic><topic>Heparin Antagonists</topic><topic>Humanities and Social Sciences</topic><topic>Humans</topic><topic>letter</topic><topic>Lipase</topic><topic>multidisciplinary</topic><topic>Old Medline</topic><topic>Phenols - pharmacology</topic><topic>Plasma</topic><topic>Science</topic><topic>Science (multidisciplinary)</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>FANTL, P</creatorcontrib><creatorcontrib>MARR, A. G. M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Nature (London)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>FANTL, P</au><au>MARR, A. G. M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Phenols as Inhibitors of the Heparin Co-factor of Plasma</atitle><jtitle>Nature (London)</jtitle><stitle>Nature</stitle><addtitle>Nature</addtitle><date>1957-11-09</date><risdate>1957</risdate><volume>180</volume><issue>4593</issue><spage>990</spage><epage>990</epage><pages>990-990</pages><issn>0028-0836</issn><eissn>1476-4687</eissn><abstract>PHENOLS counteract the antithrombic activity of plasma and serum
1
. The antithrombic activity is present in a protein fraction which also contains the co-factor required for the anticoagulant effect of heparin
2
. The antithrombic and the heparin co-factor activity are present in the α-globulin fraction of human plasma
3
. It was therefore of interest to test the influence of phenols on heparin activity in plasma.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>13483578</pmid><doi>10.1038/180990a0</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Nature (London), 1957-11, Vol.180 (4593), p.990-990 |
| issn | 0028-0836 1476-4687 |
| language | eng |
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| source | MEDLINE; Nature; Alma/SFX Local Collection |
| subjects | Heparin Heparin Antagonists Humanities and Social Sciences Humans letter Lipase multidisciplinary Old Medline Phenols - pharmacology Plasma Science Science (multidisciplinary) |
| title | Phenols as Inhibitors of the Heparin Co-factor of Plasma |
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