Recurrent and Persistent Fever in Bacterial Meningitis with Adequate Response to Antimicrobial Therapy
Abstract 106 children with bacterial meningitis and with adequate response to antimicrobial therapy were studied to determine the incidence, etiology and significance of recurrent and persistent fevers. 68 had meningococcal meningitis, 3 Hemophilus influenzae meningitis, 3 pneumococcal meningitis, a...
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| Veröffentlicht in: | Scandinavian journal of infectious diseases 1973-03, Vol.5 (1), p.23-27 |
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| container_title | Scandinavian journal of infectious diseases |
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| creator | Lipiridou, Olga Lazaridou, Sonia Manios, Sotiris |
| description | Abstract
106 children with bacterial meningitis and with adequate response to antimicrobial therapy were studied to determine the incidence, etiology and significance of recurrent and persistent fevers. 68 had meningococcal meningitis, 3 Hemophilus influenzae meningitis, 3 pneumococcal meningitis, and 32 meningitis of unknown etiology. 22% developed recurrent fever and 10% had prolonged fever. In more than half of the patients the etiology of these fevers was not determined. Phlebitis, drug fever and intercurrent infections accounted for the remaining cases. Three patients with H. influenzae meningitis had a prolonged febrile course accompanied with a slow restoration of the cerebrospinal fluid cell count. The persistence of fever in H. influenzae meningitis treated with ampicillin seems to be relatively frequent and should not be an indication for the replacement of ampicillin as long as other clinical and laboratory findings show evidence of a favorable response to therapy. |
| doi_str_mv | 10.3109/inf.1973.5.issue-1.05 |
| format | Article |
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106 children with bacterial meningitis and with adequate response to antimicrobial therapy were studied to determine the incidence, etiology and significance of recurrent and persistent fevers. 68 had meningococcal meningitis, 3 Hemophilus influenzae meningitis, 3 pneumococcal meningitis, and 32 meningitis of unknown etiology. 22% developed recurrent fever and 10% had prolonged fever. In more than half of the patients the etiology of these fevers was not determined. Phlebitis, drug fever and intercurrent infections accounted for the remaining cases. Three patients with H. influenzae meningitis had a prolonged febrile course accompanied with a slow restoration of the cerebrospinal fluid cell count. The persistence of fever in H. influenzae meningitis treated with ampicillin seems to be relatively frequent and should not be an indication for the replacement of ampicillin as long as other clinical and laboratory findings show evidence of a favorable response to therapy.</description><identifier>ISSN: 0036-5548</identifier><identifier>EISSN: 1651-1980</identifier><identifier>DOI: 10.3109/inf.1973.5.issue-1.05</identifier><identifier>PMID: 4542220</identifier><language>eng</language><publisher>England: Informa UK Ltd</publisher><subject>Adolescent ; Ampicillin - therapeutic use ; Child ; Child, Preschool ; Female ; Fever - etiology ; Haemophilus influenzae ; Humans ; Hydrocortisone - therapeutic use ; Infant ; Kanamycin - therapeutic use ; Male ; Meningitis - cerebrospinal fluid ; Meningitis - complications ; Meningitis - drug therapy ; Meningitis - mortality ; Meningitis, Haemophilus ; Meningitis, Meningococcal ; Meningitis, Pneumococcal ; Neurologic Manifestations ; Recurrence</subject><ispartof>Scandinavian journal of infectious diseases, 1973-03, Vol.5 (1), p.23-27</ispartof><rights>1973 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 1973</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c332t-3d5218916f7ed28c63c4b649258a48aa580f38ce915663f8b62ddd0b773e02153</citedby><cites>FETCH-LOGICAL-c332t-3d5218916f7ed28c63c4b649258a48aa580f38ce915663f8b62ddd0b773e02153</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.tandfonline.com/doi/pdf/10.3109/inf.1973.5.issue-1.05$$EPDF$$P50$$Ginformaworld$$H</linktopdf><linktohtml>$$Uhttps://www.tandfonline.com/doi/full/10.3109/inf.1973.5.issue-1.05$$EHTML$$P50$$Ginformaworld$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,59620,60409,61194,61375</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4542220$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lipiridou, Olga</creatorcontrib><creatorcontrib>Lazaridou, Sonia</creatorcontrib><creatorcontrib>Manios, Sotiris</creatorcontrib><title>Recurrent and Persistent Fever in Bacterial Meningitis with Adequate Response to Antimicrobial Therapy</title><title>Scandinavian journal of infectious diseases</title><addtitle>Scand J Infect Dis</addtitle><description>Abstract
106 children with bacterial meningitis and with adequate response to antimicrobial therapy were studied to determine the incidence, etiology and significance of recurrent and persistent fevers. 68 had meningococcal meningitis, 3 Hemophilus influenzae meningitis, 3 pneumococcal meningitis, and 32 meningitis of unknown etiology. 22% developed recurrent fever and 10% had prolonged fever. In more than half of the patients the etiology of these fevers was not determined. Phlebitis, drug fever and intercurrent infections accounted for the remaining cases. Three patients with H. influenzae meningitis had a prolonged febrile course accompanied with a slow restoration of the cerebrospinal fluid cell count. The persistence of fever in H. influenzae meningitis treated with ampicillin seems to be relatively frequent and should not be an indication for the replacement of ampicillin as long as other clinical and laboratory findings show evidence of a favorable response to therapy.</description><subject>Adolescent</subject><subject>Ampicillin - therapeutic use</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Female</subject><subject>Fever - etiology</subject><subject>Haemophilus influenzae</subject><subject>Humans</subject><subject>Hydrocortisone - therapeutic use</subject><subject>Infant</subject><subject>Kanamycin - therapeutic use</subject><subject>Male</subject><subject>Meningitis - cerebrospinal fluid</subject><subject>Meningitis - complications</subject><subject>Meningitis - drug therapy</subject><subject>Meningitis - mortality</subject><subject>Meningitis, Haemophilus</subject><subject>Meningitis, Meningococcal</subject><subject>Meningitis, Pneumococcal</subject><subject>Neurologic Manifestations</subject><subject>Recurrence</subject><issn>0036-5548</issn><issn>1651-1980</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1973</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1v1DAQhi0EKtvCT6jkE7ek_oi9zgmWihakIqqqnC3HnrCuEntrO1T775t0V0hc4DQazbwfehA6p6TmlLQXPvQ1bde8FrXPeYKK1kS8QisqBa1oq8hrtCKEy0qIRr1Fpzk_EEIayckJOmlEwxgjK9TfgZ1SglCwCQ7fQso-l2W9gt-QsA_4s7EFkjcD_g7Bh1---IyffNnijYPHyRTAd5B3MWTAJeJNKH70NsVukdxvIZnd_h1605shw_vjPEM_r77cX36tbn5cf7vc3FSWc1Yq7gSjqqWyX4Njykpum042LRPKNMoYoUjPlYWWCil5rzrJnHOkW685EEYFP0MfDr67FB8nyEWPPlsYBhMgTlkrRiihtJ0fxeFxLppzgl7vkh9N2mtK9MJXz3z1wlcL_cJXU02WgPNjwNSN4P6ojkDn-6fDfZbHNJqnmAani9kPMfXJBOvzYv_viI9_WWzBDGVrTQL9EKcUZn7_KfkMkrymZQ</recordid><startdate>19730301</startdate><enddate>19730301</enddate><creator>Lipiridou, Olga</creator><creator>Lazaridou, Sonia</creator><creator>Manios, Sotiris</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19730301</creationdate><title>Recurrent and Persistent Fever in Bacterial Meningitis with Adequate Response to Antimicrobial Therapy</title><author>Lipiridou, Olga ; Lazaridou, Sonia ; Manios, Sotiris</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c332t-3d5218916f7ed28c63c4b649258a48aa580f38ce915663f8b62ddd0b773e02153</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1973</creationdate><topic>Adolescent</topic><topic>Ampicillin - therapeutic use</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Female</topic><topic>Fever - etiology</topic><topic>Haemophilus influenzae</topic><topic>Humans</topic><topic>Hydrocortisone - therapeutic use</topic><topic>Infant</topic><topic>Kanamycin - therapeutic use</topic><topic>Male</topic><topic>Meningitis - cerebrospinal fluid</topic><topic>Meningitis - complications</topic><topic>Meningitis - drug therapy</topic><topic>Meningitis - mortality</topic><topic>Meningitis, Haemophilus</topic><topic>Meningitis, Meningococcal</topic><topic>Meningitis, Pneumococcal</topic><topic>Neurologic Manifestations</topic><topic>Recurrence</topic><toplevel>online_resources</toplevel><creatorcontrib>Lipiridou, Olga</creatorcontrib><creatorcontrib>Lazaridou, Sonia</creatorcontrib><creatorcontrib>Manios, Sotiris</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Scandinavian journal of infectious diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lipiridou, Olga</au><au>Lazaridou, Sonia</au><au>Manios, Sotiris</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Recurrent and Persistent Fever in Bacterial Meningitis with Adequate Response to Antimicrobial Therapy</atitle><jtitle>Scandinavian journal of infectious diseases</jtitle><addtitle>Scand J Infect Dis</addtitle><date>1973-03-01</date><risdate>1973</risdate><volume>5</volume><issue>1</issue><spage>23</spage><epage>27</epage><pages>23-27</pages><issn>0036-5548</issn><eissn>1651-1980</eissn><abstract>Abstract
106 children with bacterial meningitis and with adequate response to antimicrobial therapy were studied to determine the incidence, etiology and significance of recurrent and persistent fevers. 68 had meningococcal meningitis, 3 Hemophilus influenzae meningitis, 3 pneumococcal meningitis, and 32 meningitis of unknown etiology. 22% developed recurrent fever and 10% had prolonged fever. In more than half of the patients the etiology of these fevers was not determined. Phlebitis, drug fever and intercurrent infections accounted for the remaining cases. Three patients with H. influenzae meningitis had a prolonged febrile course accompanied with a slow restoration of the cerebrospinal fluid cell count. The persistence of fever in H. influenzae meningitis treated with ampicillin seems to be relatively frequent and should not be an indication for the replacement of ampicillin as long as other clinical and laboratory findings show evidence of a favorable response to therapy.</abstract><cop>England</cop><pub>Informa UK Ltd</pub><pmid>4542220</pmid><doi>10.3109/inf.1973.5.issue-1.05</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0036-5548 |
| ispartof | Scandinavian journal of infectious diseases, 1973-03, Vol.5 (1), p.23-27 |
| issn | 0036-5548 1651-1980 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_82010119 |
| source | Taylor & Francis; MEDLINE |
| subjects | Adolescent Ampicillin - therapeutic use Child Child, Preschool Female Fever - etiology Haemophilus influenzae Humans Hydrocortisone - therapeutic use Infant Kanamycin - therapeutic use Male Meningitis - cerebrospinal fluid Meningitis - complications Meningitis - drug therapy Meningitis - mortality Meningitis, Haemophilus Meningitis, Meningococcal Meningitis, Pneumococcal Neurologic Manifestations Recurrence |
| title | Recurrent and Persistent Fever in Bacterial Meningitis with Adequate Response to Antimicrobial Therapy |
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