The role of superoxide and singlet oxygen in lipid peroxidation promoted by xanthine oxidase

The peroxidative oxidation of extracted rat liver microsomal lipid, assayed as malondialdehyde production, can be promoted by milk xanthine oxidase in the presence of 0.2 mM FeCl 3 and 0.1 mM EDTA. The reaction is inhibited by the superoxide dismutase activity of erythrocuprein. The reaction is also...

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Veröffentlicht in:	Biochemical and biophysical research communications 1973-01, Vol.52 (3), p.1071-1078
Hauptverfasser:	Pederson, T.C., Aust, S.D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Benzofurans Chromatography, Gel Chromatography, Thin Layer Copper - analysis Cytochrome c Group - metabolism Free Radicals Lipid Metabolism Liposomes - metabolism Microsomes, Liver Milk - enzymology Oxidation-Reduction Oxidoreductases - metabolism Oxygen Rats Spectrophotometry, Atomic Superoxide Dismutase - metabolism Xanthine Oxidase - metabolism
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