A simple and rapid method for the determination of 4-hydroxy-3-methoxymandelic acid (HMMA) in urine
A simple and rapid method for the determination of urinary 4-hydroxy-3-methoxymandelic acid (HMMA) using Dowex resin is outlined. The HMMA is measured as a colour complex with diazotised p-nitroaniline. The method also allows for the determination of high HMMA levels as well as repeat estimations fr...
Gespeichert in:
| Veröffentlicht in: | Clinica chimica acta 1973-03, Vol.44 (2), p.179-182 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 182 |
|---|---|
| container_issue | 2 |
| container_start_page | 179 |
| container_title | Clinica chimica acta |
| container_volume | 44 |
| creator | Buttery, J.E. de Witt, G.F. |
| description | A simple and rapid method for the determination of urinary 4-hydroxy-3-methoxymandelic acid (HMMA) using Dowex resin is outlined. The HMMA is measured as a colour complex with diazotised
p-nitroaniline. The method also allows for the determination of high HMMA levels as well as repeat estimations from the eluate which can then be completed within 20 min. An average of six estimations can be done by one technician within 3 h. Repeatability is good and good correlation is found when compared with the method of Pisano. We have found the proposed method to be suitable for routine work. |
| doi_str_mv | 10.1016/0009-8981(73)90379-3 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_81889082</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>0009898173903793</els_id><sourcerecordid>81889082</sourcerecordid><originalsourceid>FETCH-LOGICAL-c357t-b50ada93d1f9522be5e51a4fe439b39979a0af094ebcf7dea95ad8757a5ccfb33</originalsourceid><addsrcrecordid>eNp9kEtLAzEQx4MoWh_fQCEn0UM02WyazUUoxRe0eNFzyCYTGtnd1GQr7bd3a4tHT8PwfwzzQ-iS0TtG2fieUqpIpSp2I_mtolwqwg_QiFWSE16q4hCN_iwn6DTnz2Et6Zgdo-NyrNS4ECNkJziHdtkANp3DySyDwy30i-iwjwn3C8AOekht6EwfYoejxyVZbFyK6w3h5Ne73rRDGppgsbFDwc3LfD65xaHDqxQ6OEdH3jQZLvbzDH08Pb5PX8js7fl1OpkRy4XsSS2ocUZxx7wSRVGDAMFM6aHkquZKSWWo8VSVUFsvHRgljKukkEZY62vOz9D1rneZ4tcKcq_bkC00jekgrrKuWFUpWhWDsdwZbYo5J_B6mUJr0kYzqrds9Rac3oLTkutftnrbf7XvX9UtuL_QHuagP-x0GJ78DpB0tgE6Cy4ksL12Mfx_4AfqaYjl</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>81889082</pqid></control><display><type>article</type><title>A simple and rapid method for the determination of 4-hydroxy-3-methoxymandelic acid (HMMA) in urine</title><source>Elsevier ScienceDirect Journals Complete - AutoHoldings</source><source>MEDLINE</source><creator>Buttery, J.E. ; de Witt, G.F.</creator><creatorcontrib>Buttery, J.E. ; de Witt, G.F.</creatorcontrib><description>A simple and rapid method for the determination of urinary 4-hydroxy-3-methoxymandelic acid (HMMA) using Dowex resin is outlined. The HMMA is measured as a colour complex with diazotised
p-nitroaniline. The method also allows for the determination of high HMMA levels as well as repeat estimations from the eluate which can then be completed within 20 min. An average of six estimations can be done by one technician within 3 h. Repeatability is good and good correlation is found when compared with the method of Pisano. We have found the proposed method to be suitable for routine work.</description><identifier>ISSN: 0009-8981</identifier><identifier>EISSN: 1873-3492</identifier><identifier>DOI: 10.1016/0009-8981(73)90379-3</identifier><identifier>PMID: 4699625</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Chromatography, Ion Exchange ; Disposable Equipment ; Evaluation Studies as Topic ; Humans ; Indicators and Reagents ; Mandelic Acids - urine ; Mathematics ; Methods ; Methyl Ethers - urine</subject><ispartof>Clinica chimica acta, 1973-03, Vol.44 (2), p.179-182</ispartof><rights>1973</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c357t-b50ada93d1f9522be5e51a4fe439b39979a0af094ebcf7dea95ad8757a5ccfb33</citedby><cites>FETCH-LOGICAL-c357t-b50ada93d1f9522be5e51a4fe439b39979a0af094ebcf7dea95ad8757a5ccfb33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0009-8981(73)90379-3$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,778,782,3539,27911,27912,45982</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4699625$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Buttery, J.E.</creatorcontrib><creatorcontrib>de Witt, G.F.</creatorcontrib><title>A simple and rapid method for the determination of 4-hydroxy-3-methoxymandelic acid (HMMA) in urine</title><title>Clinica chimica acta</title><addtitle>Clin Chim Acta</addtitle><description>A simple and rapid method for the determination of urinary 4-hydroxy-3-methoxymandelic acid (HMMA) using Dowex resin is outlined. The HMMA is measured as a colour complex with diazotised
p-nitroaniline. The method also allows for the determination of high HMMA levels as well as repeat estimations from the eluate which can then be completed within 20 min. An average of six estimations can be done by one technician within 3 h. Repeatability is good and good correlation is found when compared with the method of Pisano. We have found the proposed method to be suitable for routine work.</description><subject>Chromatography, Ion Exchange</subject><subject>Disposable Equipment</subject><subject>Evaluation Studies as Topic</subject><subject>Humans</subject><subject>Indicators and Reagents</subject><subject>Mandelic Acids - urine</subject><subject>Mathematics</subject><subject>Methods</subject><subject>Methyl Ethers - urine</subject><issn>0009-8981</issn><issn>1873-3492</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1973</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEtLAzEQx4MoWh_fQCEn0UM02WyazUUoxRe0eNFzyCYTGtnd1GQr7bd3a4tHT8PwfwzzQ-iS0TtG2fieUqpIpSp2I_mtolwqwg_QiFWSE16q4hCN_iwn6DTnz2Et6Zgdo-NyrNS4ECNkJziHdtkANp3DySyDwy30i-iwjwn3C8AOekht6EwfYoejxyVZbFyK6w3h5Ne73rRDGppgsbFDwc3LfD65xaHDqxQ6OEdH3jQZLvbzDH08Pb5PX8js7fl1OpkRy4XsSS2ocUZxx7wSRVGDAMFM6aHkquZKSWWo8VSVUFsvHRgljKukkEZY62vOz9D1rneZ4tcKcq_bkC00jekgrrKuWFUpWhWDsdwZbYo5J_B6mUJr0kYzqrds9Rac3oLTkutftnrbf7XvX9UtuL_QHuagP-x0GJ78DpB0tgE6Cy4ksL12Mfx_4AfqaYjl</recordid><startdate>19730314</startdate><enddate>19730314</enddate><creator>Buttery, J.E.</creator><creator>de Witt, G.F.</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19730314</creationdate><title>A simple and rapid method for the determination of 4-hydroxy-3-methoxymandelic acid (HMMA) in urine</title><author>Buttery, J.E. ; de Witt, G.F.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c357t-b50ada93d1f9522be5e51a4fe439b39979a0af094ebcf7dea95ad8757a5ccfb33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1973</creationdate><topic>Chromatography, Ion Exchange</topic><topic>Disposable Equipment</topic><topic>Evaluation Studies as Topic</topic><topic>Humans</topic><topic>Indicators and Reagents</topic><topic>Mandelic Acids - urine</topic><topic>Mathematics</topic><topic>Methods</topic><topic>Methyl Ethers - urine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Buttery, J.E.</creatorcontrib><creatorcontrib>de Witt, G.F.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Clinica chimica acta</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Buttery, J.E.</au><au>de Witt, G.F.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A simple and rapid method for the determination of 4-hydroxy-3-methoxymandelic acid (HMMA) in urine</atitle><jtitle>Clinica chimica acta</jtitle><addtitle>Clin Chim Acta</addtitle><date>1973-03-14</date><risdate>1973</risdate><volume>44</volume><issue>2</issue><spage>179</spage><epage>182</epage><pages>179-182</pages><issn>0009-8981</issn><eissn>1873-3492</eissn><abstract>A simple and rapid method for the determination of urinary 4-hydroxy-3-methoxymandelic acid (HMMA) using Dowex resin is outlined. The HMMA is measured as a colour complex with diazotised
p-nitroaniline. The method also allows for the determination of high HMMA levels as well as repeat estimations from the eluate which can then be completed within 20 min. An average of six estimations can be done by one technician within 3 h. Repeatability is good and good correlation is found when compared with the method of Pisano. We have found the proposed method to be suitable for routine work.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>4699625</pmid><doi>10.1016/0009-8981(73)90379-3</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0009-8981 |
| ispartof | Clinica chimica acta, 1973-03, Vol.44 (2), p.179-182 |
| issn | 0009-8981 1873-3492 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_81889082 |
| source | Elsevier ScienceDirect Journals Complete - AutoHoldings; MEDLINE |
| subjects | Chromatography, Ion Exchange Disposable Equipment Evaluation Studies as Topic Humans Indicators and Reagents Mandelic Acids - urine Mathematics Methods Methyl Ethers - urine |
| title | A simple and rapid method for the determination of 4-hydroxy-3-methoxymandelic acid (HMMA) in urine |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-15T11%3A12%3A44IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20simple%20and%20rapid%20method%20for%20the%20determination%20of%204-hydroxy-3-methoxymandelic%20acid%20(HMMA)%20in%20urine&rft.jtitle=Clinica%20chimica%20acta&rft.au=Buttery,%20J.E.&rft.date=1973-03-14&rft.volume=44&rft.issue=2&rft.spage=179&rft.epage=182&rft.pages=179-182&rft.issn=0009-8981&rft.eissn=1873-3492&rft_id=info:doi/10.1016/0009-8981(73)90379-3&rft_dat=%3Cproquest_cross%3E81889082%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=81889082&rft_id=info:pmid/4699625&rft_els_id=0009898173903793&rfr_iscdi=true |