Carbon monoxide and cultured rat heart cells II. Interaction of carbon monoxide and hypoxia on growth and contractile activity

Cultured rat heart muscle cells treated for 16 days with concentrations of over 19% carbon monoxide in the gas phase maintained their beating rate in direct proportion to the concentration of carbon monoxide. Reduction of oxygen to either 2.5 or 5% significantly reduced their beating rate after 6 da...

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Veröffentlicht in:	Toxicology and applied pharmacology 1973-02, Vol.24 (2), p.256-265
Hauptverfasser:	Wenzel, Duane G., Brenner, George M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Carbon Monoxide - pharmacology Cells, Cultured DNA - analysis Heart - anatomy & histology Heart - drug effects Heart - growth & development Heart - physiology Hypoxia - physiopathology In Vitro Techniques Kinetics Muscles - drug effects Myocardium - analysis Proteins - analysis Rats Time Factors
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