THE REGIONAL DISTRIBUTION OF THE POLYAMINES SPERMIDINE AND SPERMINE IN BRAIN

THE REGIONAL DISTRIBUTION OF THE POLYAMINES SPERMIDINE AND SPERMINE IN BRAIN

— The distribution in brain of the polyamines spermidine and spermine is described in the rat, dog, sheep, rabbit and in man. The distribution pattern was about the same in all the species, spermidine concentration being highest in areas rich in white matter. The concentration of spermine was lower...

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Veröffentlicht in:Journal of neurochemistry 1973-04, Vol.20 (4), p.1225-1230
Hauptverfasser: Shaw, G. G., Pateman, A. J.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Brain Chemistry
Cerebral Cortex - analysis
Chromatography, Ion Exchange
Dogs
Female
Humans
Rabbits
Rats
Sheep
Species Specificity
Spectrometry, Fluorescence
Spermidine - analysis
Spermine - analysis
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Beschreibung
Zusammenfassung:— The distribution in brain of the polyamines spermidine and spermine is described in the rat, dog, sheep, rabbit and in man. The distribution pattern was about the same in all the species, spermidine concentration being highest in areas rich in white matter. The concentration of spermine was lower than that of spermidine and showed less variation from area to area. Rat brain polyamine content was the same in rats killed by decapitation as in those killed by rapid freezing in liquid nitrogen and was also unchanged up to 48 h after the death of the animal.
ISSN:0022-3042
1471-4159
DOI:10.1111/j.1471-4159.1973.tb00091.x