Livedo racemosa, secondary to drug-induced systemic lupus erythematosus
We present a 40-year-old man with erythematous-to-violaceous, broken, reticulated patches on the upper chest, back, and extremities, which is consistent with livedo racemosa. The cutaneous findings appeared after an increase in dilantin dose and subsequently improved after a reduction in dilantin do...
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| Veröffentlicht in: | Dermatology online journal 2010-11, Vol.16 (11), p.24-24 |
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| creator | Defelice, Taylor Lu, Phoebe Loyd, Aaron Patel, Rishi Franks, Jr, Andrew G |
| description | We present a 40-year-old man with erythematous-to-violaceous, broken, reticulated patches on the upper chest, back, and extremities, which is consistent with livedo racemosa. The cutaneous findings appeared after an increase in dilantin dose and subsequently improved after a reduction in dilantin dose. Furthermore, antinuclear antibodies and antihistone antibodies were detected. We therefore believe that the livedo racemosa is a cutaneous manifestation of a drug-induced systemic lupus erythematosus. We review the distinctive features of livedo racemosa as well as its associations with several disorders. Although there are no effective treatments for livedo racemosa, patients often are placed on low-dose aspirin and counseled to avoid smoking in an effort to protect against their increased risk of stroke and arterial thrombosis. |
| doi_str_mv | 10.5070/D38289G3RX |
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The cutaneous findings appeared after an increase in dilantin dose and subsequently improved after a reduction in dilantin dose. Furthermore, antinuclear antibodies and antihistone antibodies were detected. We therefore believe that the livedo racemosa is a cutaneous manifestation of a drug-induced systemic lupus erythematosus. We review the distinctive features of livedo racemosa as well as its associations with several disorders. 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The cutaneous findings appeared after an increase in dilantin dose and subsequently improved after a reduction in dilantin dose. Furthermore, antinuclear antibodies and antihistone antibodies were detected. We therefore believe that the livedo racemosa is a cutaneous manifestation of a drug-induced systemic lupus erythematosus. We review the distinctive features of livedo racemosa as well as its associations with several disorders. 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| subjects | Adult Aspirin - therapeutic use Autoantibodies - blood Histones - blood Histones - immunology Humans Livedo Reticularis - diagnosis Lupus Erythematosus, Systemic - chemically induced Lupus Erythematosus, Systemic - complications Male Phenytoin - adverse effects Phenytoin - therapeutic use Skin Diseases, Vascular - diagnosis Skin Diseases, Vascular - etiology Smoking - adverse effects |
| title | Livedo racemosa, secondary to drug-induced systemic lupus erythematosus |
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