Protein tyrosine phosphatase activity is necessary for E-cadherin-activated Src signaling

Co‐operation between cadherin adhesion molecules and the cytoskeleton is a key aspect of tissue morphogenesis that is mediated by cortical signaling at adhesive junctions. One such signal is the non‐receptor tyrosine kinase, Src, which acts in several pathways at epithelial junctions, including E‐ca...

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Veröffentlicht in:	Cytoskeleton (Hoboken, N.J.) N.J.), 2011-01, Vol.68 (1), p.32-43
Hauptverfasser:	McLachlan, Robert W., Yap, Alpha S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adherens Junctions - drug effects Adherens Junctions - metabolism Cadherins - metabolism Cell Line, Tumor Cytoskeleton - metabolism E-cadherin Humans myosin II Nonmuscle Myosin Type IIB - metabolism protein tyrosine phosphatase Protein Tyrosine Phosphatases - metabolism Signal Transduction - physiology Src src-Family Kinases - metabolism Vanadates - pharmacology ZO-1
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