Secretion of Aldosterone by the Zona Glomerulosa of Rat Adrenal Glands Incubated in Vitro.
Conclusion Rat adrenal glands incubated in vitro release aldosterone at the rate of 0.66 μg/100 mg of tissue per hour. Decapsulated rat adrenal glands secrete only negligible amounts of the hormone. Comparison of aldosterone production between decapsulated rat adrenals and their capsules shows that...
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| Veröffentlicht in: | Experimental biology and medicine (Maywood, N.J.) N.J.), 1956-05, Vol.92 (1), p.154-158 |
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| container_issue | 1 |
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| container_title | Experimental biology and medicine (Maywood, N.J.) |
| container_volume | 92 |
| creator | Giroud, C. J. P. Stachenko, J. Venning, E. H. |
| description | Conclusion
Rat adrenal glands incubated in vitro release aldosterone at the rate of 0.66 μg/100 mg of tissue per hour. Decapsulated rat adrenal glands secrete only negligible amounts of the hormone. Comparison of aldosterone production between decapsulated rat adrenals and their capsules shows that most of the hormone is secreted by the capsular portion which contains the cells of the zona glomerulosa. These findings are strong evidence that the principal site of aldosterone secretion in the rat adrenal is the zona glomerulosa. |
| doi_str_mv | 10.3181/00379727-92-22416 |
| format | Article |
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Rat adrenal glands incubated in vitro release aldosterone at the rate of 0.66 μg/100 mg of tissue per hour. Decapsulated rat adrenal glands secrete only negligible amounts of the hormone. Comparison of aldosterone production between decapsulated rat adrenals and their capsules shows that most of the hormone is secreted by the capsular portion which contains the cells of the zona glomerulosa. These findings are strong evidence that the principal site of aldosterone secretion in the rat adrenal is the zona glomerulosa.</description><identifier>ISSN: 0037-9727</identifier><identifier>ISSN: 1535-3702</identifier><identifier>EISSN: 1535-3699</identifier><identifier>DOI: 10.3181/00379727-92-22416</identifier><identifier>PMID: 13336105</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Adrenal Cortex ; Adrenal Cortex Hormones ; Aldosterone ; Animals ; In Vitro Techniques ; Old Medline ; Rats ; Zona Glomerulosa</subject><ispartof>Experimental biology and medicine (Maywood, N.J.), 1956-05, Vol.92 (1), p.154-158</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c317t-d2fc90579bc73add1c71b86adba104988bb2f1cdc52d9e987c4558cbd21c30243</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,782,786,27931,27932</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/13336105$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Giroud, C. J. P.</creatorcontrib><creatorcontrib>Stachenko, J.</creatorcontrib><creatorcontrib>Venning, E. H.</creatorcontrib><title>Secretion of Aldosterone by the Zona Glomerulosa of Rat Adrenal Glands Incubated in Vitro.</title><title>Experimental biology and medicine (Maywood, N.J.)</title><addtitle>Proc Soc Exp Biol Med</addtitle><description>Conclusion
Rat adrenal glands incubated in vitro release aldosterone at the rate of 0.66 μg/100 mg of tissue per hour. Decapsulated rat adrenal glands secrete only negligible amounts of the hormone. Comparison of aldosterone production between decapsulated rat adrenals and their capsules shows that most of the hormone is secreted by the capsular portion which contains the cells of the zona glomerulosa. These findings are strong evidence that the principal site of aldosterone secretion in the rat adrenal is the zona glomerulosa.</description><subject>Adrenal Cortex</subject><subject>Adrenal Cortex Hormones</subject><subject>Aldosterone</subject><subject>Animals</subject><subject>In Vitro Techniques</subject><subject>Old Medline</subject><subject>Rats</subject><subject>Zona Glomerulosa</subject><issn>0037-9727</issn><issn>1535-3702</issn><issn>1535-3699</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1956</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kDtPwzAUhS0EoqXwA1iQJ7YUX7uO47GqoFSqhMRr6GL5FUiVxsVOhv57UlrExnSH852jqw-hayBjBgXcEcKEFFRkkmaUTiA_QUPgjGcsl_IUDfd5tgcG6CKlNSHABc3P0QAYYzkQPkSrF2-jb6vQ4FDiae1Can0Mjcdmh9tPj1eh0Xheh42PXR2S3mPPusVTF32j6z7SjUt40djO6NY7XDX4vWpjGF-is1LXyV8d7wi9Pdy_zh6z5dN8MZsuM8tAtJmjpZWEC2msYNo5sAJMkWtnNJCJLApjaAnWWU6d9LIQdsJ5YY2jYBmhEzZCt4fdbQxfnU-t2lTJ-rp_zIcuqQIKTvNc9CAcQBtDStGXahurjY47BUTthapfoUpS9SO079wcxzuz8e6vcTTYA-MDkPSHV-vQxd5K-mfxG3L6ffU</recordid><startdate>195605</startdate><enddate>195605</enddate><creator>Giroud, C. J. P.</creator><creator>Stachenko, J.</creator><creator>Venning, E. H.</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>195605</creationdate><title>Secretion of Aldosterone by the Zona Glomerulosa of Rat Adrenal Glands Incubated in Vitro.</title><author>Giroud, C. J. P. ; Stachenko, J. ; Venning, E. H.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c317t-d2fc90579bc73add1c71b86adba104988bb2f1cdc52d9e987c4558cbd21c30243</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1956</creationdate><topic>Adrenal Cortex</topic><topic>Adrenal Cortex Hormones</topic><topic>Aldosterone</topic><topic>Animals</topic><topic>In Vitro Techniques</topic><topic>Old Medline</topic><topic>Rats</topic><topic>Zona Glomerulosa</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Giroud, C. J. P.</creatorcontrib><creatorcontrib>Stachenko, J.</creatorcontrib><creatorcontrib>Venning, E. H.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Giroud, C. J. P.</au><au>Stachenko, J.</au><au>Venning, E. H.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Secretion of Aldosterone by the Zona Glomerulosa of Rat Adrenal Glands Incubated in Vitro.</atitle><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle><addtitle>Proc Soc Exp Biol Med</addtitle><date>1956-05</date><risdate>1956</risdate><volume>92</volume><issue>1</issue><spage>154</spage><epage>158</epage><pages>154-158</pages><issn>0037-9727</issn><issn>1535-3702</issn><eissn>1535-3699</eissn><abstract>Conclusion
Rat adrenal glands incubated in vitro release aldosterone at the rate of 0.66 μg/100 mg of tissue per hour. Decapsulated rat adrenal glands secrete only negligible amounts of the hormone. Comparison of aldosterone production between decapsulated rat adrenals and their capsules shows that most of the hormone is secreted by the capsular portion which contains the cells of the zona glomerulosa. These findings are strong evidence that the principal site of aldosterone secretion in the rat adrenal is the zona glomerulosa.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>13336105</pmid><doi>10.3181/00379727-92-22416</doi><tpages>5</tpages></addata></record> |
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| identifier | ISSN: 0037-9727 |
| ispartof | Experimental biology and medicine (Maywood, N.J.), 1956-05, Vol.92 (1), p.154-158 |
| issn | 0037-9727 1535-3702 1535-3699 |
| language | eng |
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| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Adrenal Cortex Adrenal Cortex Hormones Aldosterone Animals In Vitro Techniques Old Medline Rats Zona Glomerulosa |
| title | Secretion of Aldosterone by the Zona Glomerulosa of Rat Adrenal Glands Incubated in Vitro. |
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