IL-25 in Atopic Dermatitis: A Possible Link between Inflammation and Skin Barrier Dysfunction?

Atopic dermatitis (AD) is a common skin disease associated with a TH2 response and increased levels of TH2-associated cytokines and IgE. The mechanisms resulting in skewing the immune response in a TH2 direction in AD are not fully elucidated. However, such skewing has recently been associated with...

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Veröffentlicht in:	Journal of investigative dermatology 2011-01, Vol.131 (1), p.150-157
Hauptverfasser:	Hvid, Malene, Vestergaard, Christian, Kemp, Kaare, Christensen, Gitte B., Deleuran, Bent, Deleuran, Mette
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Allergic diseases Biological and medical sciences Cells, Cultured Dendritic Cells - cytology Dendritic Cells - immunology Dendritic Cells - metabolism Dermatitis, Atopic - immunology Dermatitis, Atopic - metabolism Dermatology Flow Cytometry HLA-DR Antigens - immunology HLA-DR Antigens - metabolism Humans Immunopathology Interleukin-17 - genetics Interleukin-17 - immunology Interleukin-17 - metabolism Intermediate Filament Proteins - immunology Intermediate Filament Proteins - metabolism Keratinocytes - cytology Keratinocytes - immunology Keratinocytes - metabolism Medical sciences Permeability Receptors, Interleukin-17 - immunology Receptors, Interleukin-17 - metabolism RNA, Messenger - metabolism Skin allergic diseases. Stinging insect allergies Th2 Cells - immunology Th2 Cells - metabolism
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