Some biochemical changes in penicillin-inhibited Escherichia coli cells

Some biochemical changes in penicillin-inhibited Escherichia coli cells

Actively growing cultures of Escherichia coli A.T.C.C. 9723 treated with minimum bacteriostatic concentrations of penicillin for short periods of time maintain the ability to synthesize protein which appears in the extracellular medium. At the same time, there is accumulation of an extracellular sub...

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Veröffentlicht in:Archives of biochemistry and biophysics 1956-03, Vol.61 (1), p.84-88
1. Verfasser: Binkley, S.B.
Format: Artikel
Sprache:eng
Schlagworte:
Escherichia coli - drug effects
Old Medline
Penicillins - pharmacology
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Zusammenfassung:Actively growing cultures of Escherichia coli A.T.C.C. 9723 treated with minimum bacteriostatic concentrations of penicillin for short periods of time maintain the ability to synthesize protein which appears in the extracellular medium. At the same time, there is accumulation of an extracellular substance having high absorption at 260 mμ. This substance has been tentatively identified as uracil.
ISSN:0003-9861
1096-0384
DOI:10.1016/0003-9861(56)90318-6