Ion channel screening plates: design, construction, and maintenance

Ion channels have provided a diverse set of therapeutic targets across all areas of the pharmaceutical industry. Many companies are pursuing this unique class of targets for areas of unmet medical need such as neuropathic and inflammatory pains. In the past, focused library screening sets had been d...

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Veröffentlicht in:	Assay and drug development technologies 2010-08, Vol.8 (4), p.504-511
Hauptverfasser:	Mayer, Scott C, Butera, John A, Diller, David J, Dunlop, John, Ellingboe, John, Fan, Kristi Yi, Kaftan, Edward, Mekonnen, Belew, Mobilio, Dominick, Paslay, Jeff, Tawa, Gregory, Vasilyev, Dmitry, Bowlby, Mark R
Format:	Artikel
Sprache:	eng
Schlagworte:	Drug Design Drug Evaluation, Preclinical - methods Drugs Gene expression Genetic aspects Ion Channel Gating Ion channels Ion Channels - analysis Ion Channels - metabolism Models, Molecular Molecular Targeted Therapy Physiological aspects Product/Service Evaluations Small Molecule Libraries
Online-Zugang:	Volltext
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