Overcoming remyelination failure in multiple sclerosis and other myelin disorders

Protecting axons from degeneration represents a major unmet need in the treatment of myelin disorders and especially the currently untreatable secondary progressive stages of multiple sclerosis (MS). Several lines of evidence indicate that ensuring myelin sheaths are restored to demyelinated axons,...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Experimental neurology 2010-09, Vol.225 (1), p.18-23
Hauptverfasser:	Fancy, Stephen P.J., Kotter, Mark R., Harrington, Emily P., Huang, Jeffrey K., Zhao, Chao, Rowitch, David H., Franklin, Robin J.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Differentiation - physiology Humans Multiple sclerosis Multiple Sclerosis - metabolism Multiple Sclerosis - pathology Multiple Sclerosis - physiopathology Myelin Nerve Fibers, Myelinated - metabolism Nerve Fibers, Myelinated - pathology Nerve Regeneration - drug effects Nerve Regeneration - physiology Notch Oligodendroglia - metabolism Oligodendroglia - pathology Periventricular leukomalacia Regeneration Remyelination Signal Transduction - physiology Stem cell Stem Cells - metabolism Stem Cells - pathology wnt
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!