Unbalanced translocation der(1;7)(q10;p10) defines a unique clinicopathological subgroup of myeloid neoplasms

The unbalanced translocation, der(1;7)(q10;p10), is one of the characteristic cytogenetic abnormalities found in myelodysplastic syndromes (MDS) and other myeloid neoplasms. Although described frequently with very poor clinical outcome and possible relationship with monosomy 7 or 7q- (-7/7q-), this...

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Veröffentlicht in:	Leukemia 2007-05, Vol.21 (5), p.992-997
Hauptverfasser:	SANADA, M, UIKE, N, MITANI, K, OGAWA, S, OHYASHIKI, K, OZAWA, K, LILI, W, HANGAISHI, A, KANDA, Y, CHIBA, S, KUROKAWA, M, OMINE, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormalities Acute myeloid leukemia Adolescent Adult Aged Aged, 80 and over Biological and medical sciences Bone marrow Chromosome Aberrations Chromosomes Chromosomes, Human, Pair 1 Chromosomes, Human, Pair 7 Cytogenetics Female Hematologic and hematopoietic diseases Hematology Hematopoietic Stem Cell Transplantation Hemoglobin Humans Karyotypes Leukemia Leukemia, Myeloid, Acute - genetics Leukemia, Myeloid, Acute - pathology Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Male Medical genetics Medical prognosis Medical schools Medical sciences Medicine Middle Aged Monosomy Mutation Myelodysplastic syndrome Myelodysplastic syndromes Myelodysplastic Syndromes - genetics Myelodysplastic Syndromes - pathology Myeloproliferative Disorders - genetics Myeloproliferative Disorders - pathology Neoplasms Oncology Radiation therapy Retrospective Studies Subgroups Translocation Translocation, Genetic Trisomy Tumors
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