Establishment and comprehensive analysis of a new human transformed follicular lymphoma B cell line, Tat-1

A spontaneously EBV transformed follicular lymphoma (FL) cell line, Tat-1, was established from the lymph node biopsy specimen of a patient with B cell FL, grade 1 in transformation to high grade disease. Tat-1 cells expressed lymphoid markers and developed tumor masses in immunodeficient mice. Bcl-...

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Veröffentlicht in:	Leukemia 2002-02, Vol.16 (2), p.276-283
Hauptverfasser:	DENYSSEVYCH, T, LESTOU, V. S, KNESEVICH, S, ROBICHAUD, M, SALSKI, C, TAN, R, GASCOYNE, R. D, HORSMAN, D. E, MAYER, L. D
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormalities Animals Apoptosis ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism Bax protein Bcl-2 protein bcl-2-Associated X Protein Bcl-x protein Biological and medical sciences Biomarkers, Tumor - analysis Biopsy Burkitt Lymphoma - genetics Burkitt Lymphoma - pathology Burkitt Lymphoma - virology c-Myc protein Cell Transformation, Viral Chromosome 1 Chromosome Aberrations Chromosome Painting Chromosomes Chromosomes, Human, Pair 14 - genetics Chromosomes, Human, Pair 18 - genetics Cytogenetics Deregulation Disease Progression DNA-Binding Proteins - genetics Doxorubicin - metabolism Drug Resistance, Multiple - genetics Drug Resistance, Neoplasm - genetics Epstein-Barr virus Epstein-Barr Virus Infections - pathology Fatal Outcome Female Flow Cytometry Genes, Tumor Suppressor Heavy chains Hematologic and hematopoietic diseases Herpesvirus 4, Human - isolation & purification Humans Immunodeficiency Immunoglobulins Karyotyping Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Loci Lymph nodes Lymphoma Lymphoma, Follicular - genetics Lymphoma, Follicular - pathology Lymphoma, Follicular - virology Lymphoma, Non-Hodgkin - genetics Lymphoma, Non-Hodgkin - pathology Lymphoma, Non-Hodgkin - virology Male Medical sciences Mice Mice, Knockout Middle Aged Multidrug resistance Myc protein Neoplasm Proteins - analysis Neoplasm Transplantation Nuclear Proteins Oncogenes p53 Protein Phenotypes Proteins Proto-Oncogene Proteins - analysis Proto-Oncogene Proteins c-bcl-2 - analysis Recombination Translocation, Genetic Transplantation, Heterologous Tumor Cells, Cultured - chemistry Tumor Cells, Cultured - ultrastructure Tumor Suppressor Protein p53 - analysis Tumors Western blotting
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