Balanced polymorphism in bottlenecked populations: The case of the CCR5 5a super(2) cis-regulatory region in Amazonian Amerindians

The 5a super(2) cis-regulatory region of the CCR5 gene exhibits a strong signature of balancing selection in several human populations. Here we analyze the polymorphism of this region in Amerindians from Amazonia, who have a complex demographic history, including recent bottlenecks that are known to...

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Veröffentlicht in:	Human immunology 2010-09, Vol.71 (9), p.922-928
Hauptverfasser:	Ramalho, Rodrigo F, Santos, Eduardo JM, Guerreiro, Joao F, Meyer, Diogo
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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