Pneumocystis pneumonia in the dog
Pneumonia caused by Pneumocystis carinii occurred in 6 young, male, miniature dachshunds producing severe dyspnoea, although the dogs were afebrile and otherwise alert. The diffuse nature of the pulmonary disease and the resultant cardiac enlargement were visible radiographically. Diagnosis was conf...
Gespeichert in:
Veröffentlicht in: | Journal of comparative pathology 1972-01, Vol.82 (4), p.447,IN11,453-452,IN15,453 |
---|---|
Hauptverfasser: | , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 452,IN15,453 |
---|---|
container_issue | 4 |
container_start_page | 447,IN11,453 |
container_title | Journal of comparative pathology |
container_volume | 82 |
creator | Farrow, B.R.H. Watson, A.D.J. Hartley, W.J. Huxtable, C.R.R. |
description | Pneumonia caused by
Pneumocystis carinii occurred in 6 young, male, miniature dachshunds producing severe dyspnoea, although the dogs were afebrile and otherwise alert. The diffuse nature of the pulmonary disease and the resultant cardiac enlargement were visible radiographically. Diagnosis was confirmed by lung biopsy in 3 of the dogs and at post-mortem examination in the remaining 3. Specific treatment with pentamidine isethionate was attempted in one of the dogs and resulted in considerable improvement although a severe reaction was produced at the injection site.
The post-mortem appearance of the lungs was characteristic as were the histological changes. Electronmicroscopic examination of portions of lung from one dog allowed detailed examination of the morphology of the organism.
Examination of the 5 available pedigrees indicated that the dogs were closely related, suggesting the possible existence of an heritable immune-deficiency state which allowed the organisms to become pathogenic. |
doi_str_mv | 10.1016/0021-9975(72)90044-8 |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_81709414</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>0021997572900448</els_id><sourcerecordid>81709414</sourcerecordid><originalsourceid>FETCH-LOGICAL-c381t-5333bec28c50995fad4d6e24c53b5ca3ed36426213a30ebd1a1cf8f27712b54d3</originalsourceid><addsrcrecordid>eNp9kE1Lw0AQhhdRaq3-A8V4ET1Ed_Yj2VwEKX5BQUF7Xja7k7rSJDWbCP33pk3x6GkY5pl35n0JOQV6AxSSW0oZxFmWyquUXWeUChGrPTIGyVnMgWX7ZPyHHJKjEL4opUpJNiIjwRIJiRqTi7cKu7K269D6EK22TeVN5Kuo_cTI1YtjclCYZcCTXZ2Q-ePDx_Q5nr0-vUzvZ7HlCtpYcs5ztExZSbNMFsYJlyATVvJcWsPR8aS_yoAbTjF3YMAWqmBpCiyXwvEJuRx0V0393WFodemDxeXSVFh3QStIaSZA9KAYQNvUITRY6FXjS9OsNVC9SUZvbOuNbZ0yvU1Gq37tbKff5SW6v6VdFP38fJgXptZm0fig5--MAqeMceg1euJuILCP4cdjo4P1WFl0vkHbalf7_1_4Bc1pebU</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>81709414</pqid></control><display><type>article</type><title>Pneumocystis pneumonia in the dog</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals Complete</source><creator>Farrow, B.R.H. ; Watson, A.D.J. ; Hartley, W.J. ; Huxtable, C.R.R.</creator><creatorcontrib>Farrow, B.R.H. ; Watson, A.D.J. ; Hartley, W.J. ; Huxtable, C.R.R.</creatorcontrib><description>Pneumonia caused by
Pneumocystis carinii occurred in 6 young, male, miniature dachshunds producing severe dyspnoea, although the dogs were afebrile and otherwise alert. The diffuse nature of the pulmonary disease and the resultant cardiac enlargement were visible radiographically. Diagnosis was confirmed by lung biopsy in 3 of the dogs and at post-mortem examination in the remaining 3. Specific treatment with pentamidine isethionate was attempted in one of the dogs and resulted in considerable improvement although a severe reaction was produced at the injection site.
The post-mortem appearance of the lungs was characteristic as were the histological changes. Electronmicroscopic examination of portions of lung from one dog allowed detailed examination of the morphology of the organism.
Examination of the 5 available pedigrees indicated that the dogs were closely related, suggesting the possible existence of an heritable immune-deficiency state which allowed the organisms to become pathogenic.</description><identifier>ISSN: 0021-9975</identifier><identifier>EISSN: 1532-3129</identifier><identifier>DOI: 10.1016/0021-9975(72)90044-8</identifier><identifier>PMID: 4265168</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Amidines - therapeutic use ; animal diseases ; animal health ; Animals ; Biopsy ; Cardiomegaly - diagnostic imaging ; Dog Diseases - diagnostic imaging ; Dog Diseases - drug therapy ; Dog Diseases - pathology ; Dogs ; Immunologic Deficiency Syndromes ; Lung - pathology ; Male ; Microscopy, Electron ; Pneumonia, Pneumocystis - diagnostic imaging ; Pneumonia, Pneumocystis - drug therapy ; Pneumonia, Pneumocystis - pathology ; Pneumonia, Pneumocystis - veterinary ; Pulmonary Alveoli - pathology ; Radiography, Thoracic</subject><ispartof>Journal of comparative pathology, 1972-01, Vol.82 (4), p.447,IN11,453-452,IN15,453</ispartof><rights>1972</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c381t-5333bec28c50995fad4d6e24c53b5ca3ed36426213a30ebd1a1cf8f27712b54d3</citedby><cites>FETCH-LOGICAL-c381t-5333bec28c50995fad4d6e24c53b5ca3ed36426213a30ebd1a1cf8f27712b54d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0021-9975(72)90044-8$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4265168$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Farrow, B.R.H.</creatorcontrib><creatorcontrib>Watson, A.D.J.</creatorcontrib><creatorcontrib>Hartley, W.J.</creatorcontrib><creatorcontrib>Huxtable, C.R.R.</creatorcontrib><title>Pneumocystis pneumonia in the dog</title><title>Journal of comparative pathology</title><addtitle>J Comp Pathol</addtitle><description>Pneumonia caused by
Pneumocystis carinii occurred in 6 young, male, miniature dachshunds producing severe dyspnoea, although the dogs were afebrile and otherwise alert. The diffuse nature of the pulmonary disease and the resultant cardiac enlargement were visible radiographically. Diagnosis was confirmed by lung biopsy in 3 of the dogs and at post-mortem examination in the remaining 3. Specific treatment with pentamidine isethionate was attempted in one of the dogs and resulted in considerable improvement although a severe reaction was produced at the injection site.
The post-mortem appearance of the lungs was characteristic as were the histological changes. Electronmicroscopic examination of portions of lung from one dog allowed detailed examination of the morphology of the organism.
Examination of the 5 available pedigrees indicated that the dogs were closely related, suggesting the possible existence of an heritable immune-deficiency state which allowed the organisms to become pathogenic.</description><subject>Amidines - therapeutic use</subject><subject>animal diseases</subject><subject>animal health</subject><subject>Animals</subject><subject>Biopsy</subject><subject>Cardiomegaly - diagnostic imaging</subject><subject>Dog Diseases - diagnostic imaging</subject><subject>Dog Diseases - drug therapy</subject><subject>Dog Diseases - pathology</subject><subject>Dogs</subject><subject>Immunologic Deficiency Syndromes</subject><subject>Lung - pathology</subject><subject>Male</subject><subject>Microscopy, Electron</subject><subject>Pneumonia, Pneumocystis - diagnostic imaging</subject><subject>Pneumonia, Pneumocystis - drug therapy</subject><subject>Pneumonia, Pneumocystis - pathology</subject><subject>Pneumonia, Pneumocystis - veterinary</subject><subject>Pulmonary Alveoli - pathology</subject><subject>Radiography, Thoracic</subject><issn>0021-9975</issn><issn>1532-3129</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1972</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1Lw0AQhhdRaq3-A8V4ET1Ed_Yj2VwEKX5BQUF7Xja7k7rSJDWbCP33pk3x6GkY5pl35n0JOQV6AxSSW0oZxFmWyquUXWeUChGrPTIGyVnMgWX7ZPyHHJKjEL4opUpJNiIjwRIJiRqTi7cKu7K269D6EK22TeVN5Kuo_cTI1YtjclCYZcCTXZ2Q-ePDx_Q5nr0-vUzvZ7HlCtpYcs5ztExZSbNMFsYJlyATVvJcWsPR8aS_yoAbTjF3YMAWqmBpCiyXwvEJuRx0V0393WFodemDxeXSVFh3QStIaSZA9KAYQNvUITRY6FXjS9OsNVC9SUZvbOuNbZ0yvU1Gq37tbKff5SW6v6VdFP38fJgXptZm0fig5--MAqeMceg1euJuILCP4cdjo4P1WFl0vkHbalf7_1_4Bc1pebU</recordid><startdate>19720101</startdate><enddate>19720101</enddate><creator>Farrow, B.R.H.</creator><creator>Watson, A.D.J.</creator><creator>Hartley, W.J.</creator><creator>Huxtable, C.R.R.</creator><general>Elsevier Ltd</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19720101</creationdate><title>Pneumocystis pneumonia in the dog</title><author>Farrow, B.R.H. ; Watson, A.D.J. ; Hartley, W.J. ; Huxtable, C.R.R.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c381t-5333bec28c50995fad4d6e24c53b5ca3ed36426213a30ebd1a1cf8f27712b54d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1972</creationdate><topic>Amidines - therapeutic use</topic><topic>animal diseases</topic><topic>animal health</topic><topic>Animals</topic><topic>Biopsy</topic><topic>Cardiomegaly - diagnostic imaging</topic><topic>Dog Diseases - diagnostic imaging</topic><topic>Dog Diseases - drug therapy</topic><topic>Dog Diseases - pathology</topic><topic>Dogs</topic><topic>Immunologic Deficiency Syndromes</topic><topic>Lung - pathology</topic><topic>Male</topic><topic>Microscopy, Electron</topic><topic>Pneumonia, Pneumocystis - diagnostic imaging</topic><topic>Pneumonia, Pneumocystis - drug therapy</topic><topic>Pneumonia, Pneumocystis - pathology</topic><topic>Pneumonia, Pneumocystis - veterinary</topic><topic>Pulmonary Alveoli - pathology</topic><topic>Radiography, Thoracic</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Farrow, B.R.H.</creatorcontrib><creatorcontrib>Watson, A.D.J.</creatorcontrib><creatorcontrib>Hartley, W.J.</creatorcontrib><creatorcontrib>Huxtable, C.R.R.</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of comparative pathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Farrow, B.R.H.</au><au>Watson, A.D.J.</au><au>Hartley, W.J.</au><au>Huxtable, C.R.R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pneumocystis pneumonia in the dog</atitle><jtitle>Journal of comparative pathology</jtitle><addtitle>J Comp Pathol</addtitle><date>1972-01-01</date><risdate>1972</risdate><volume>82</volume><issue>4</issue><spage>447,IN11,453</spage><epage>452,IN15,453</epage><pages>447,IN11,453-452,IN15,453</pages><issn>0021-9975</issn><eissn>1532-3129</eissn><abstract>Pneumonia caused by
Pneumocystis carinii occurred in 6 young, male, miniature dachshunds producing severe dyspnoea, although the dogs were afebrile and otherwise alert. The diffuse nature of the pulmonary disease and the resultant cardiac enlargement were visible radiographically. Diagnosis was confirmed by lung biopsy in 3 of the dogs and at post-mortem examination in the remaining 3. Specific treatment with pentamidine isethionate was attempted in one of the dogs and resulted in considerable improvement although a severe reaction was produced at the injection site.
The post-mortem appearance of the lungs was characteristic as were the histological changes. Electronmicroscopic examination of portions of lung from one dog allowed detailed examination of the morphology of the organism.
Examination of the 5 available pedigrees indicated that the dogs were closely related, suggesting the possible existence of an heritable immune-deficiency state which allowed the organisms to become pathogenic.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>4265168</pmid><doi>10.1016/0021-9975(72)90044-8</doi><tpages>7</tpages></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0021-9975 |
ispartof | Journal of comparative pathology, 1972-01, Vol.82 (4), p.447,IN11,453-452,IN15,453 |
issn | 0021-9975 1532-3129 |
language | eng |
recordid | cdi_proquest_miscellaneous_81709414 |
source | MEDLINE; Elsevier ScienceDirect Journals Complete |
subjects | Amidines - therapeutic use animal diseases animal health Animals Biopsy Cardiomegaly - diagnostic imaging Dog Diseases - diagnostic imaging Dog Diseases - drug therapy Dog Diseases - pathology Dogs Immunologic Deficiency Syndromes Lung - pathology Male Microscopy, Electron Pneumonia, Pneumocystis - diagnostic imaging Pneumonia, Pneumocystis - drug therapy Pneumonia, Pneumocystis - pathology Pneumonia, Pneumocystis - veterinary Pulmonary Alveoli - pathology Radiography, Thoracic |
title | Pneumocystis pneumonia in the dog |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-04T11%3A23%3A10IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Pneumocystis%20pneumonia%20in%20the%20dog&rft.jtitle=Journal%20of%20comparative%20pathology&rft.au=Farrow,%20B.R.H.&rft.date=1972-01-01&rft.volume=82&rft.issue=4&rft.spage=447,IN11,453&rft.epage=452,IN15,453&rft.pages=447,IN11,453-452,IN15,453&rft.issn=0021-9975&rft.eissn=1532-3129&rft_id=info:doi/10.1016/0021-9975(72)90044-8&rft_dat=%3Cproquest_cross%3E81709414%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=81709414&rft_id=info:pmid/4265168&rft_els_id=0021997572900448&rfr_iscdi=true |