Graft-versus-Host Reactivity of Lymphoid Cells inhibited by Anti-recognition Structure Serum
F1 hybrid animals injected with parental strain lymphoid cells were reported to develop antibodies that specifically react with parental alloantigen receptors or "recognition structures" (RS)1,2. The effect of such "anti-recognition structure" (anti-RS) sera was demonstrated by b...
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| Veröffentlicht in: | Nature. New biology (London) 1972-12, Vol.240 (102), p.214-215 |
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| container_title | Nature. New biology (London) |
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| creator | JOLLER, P. W |
| description | F1 hybrid animals injected with parental strain lymphoid cells were reported to develop antibodies that specifically react with parental alloantigen receptors or "recognition structures" (RS)1,2. The effect of such "anti-recognition structure" (anti-RS) sera was demonstrated by blocking of the recognition event in vitro, using the PAR assay3. It seemed important to find out whether anti-RS sera were also active in vivo. For this purpose, inhibition by an anti-RS serum of the lethal graft-versus-host activity of parental lymphoid cells injected into newborn F1 hybrids was attempted. |
| doi_str_mv | 10.1038/newbio240214a0 |
| format | Article |
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For this purpose, inhibition by an anti-RS serum of the lethal graft-versus-host activity of parental lymphoid cells injected into newborn F1 hybrids was attempted.</description><identifier>ISSN: 0090-0028</identifier><identifier>EISSN: 2058-1092</identifier><identifier>DOI: 10.1038/newbio240214a0</identifier><identifier>PMID: 4404910</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>Animals ; Biomedical and Life Sciences ; Graft vs Host Reaction ; Guinea Pigs - immunology ; Immune Sera ; Isoantigens ; letters-to-editor ; Life Sciences ; Lymphocytes - immunology ; Mice ; Mice, Inbred A ; Mice, Inbred C57BL ; Spleen - cytology ; Spleen - immunology</subject><ispartof>Nature. 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For this purpose, inhibition by an anti-RS serum of the lethal graft-versus-host activity of parental lymphoid cells injected into newborn F1 hybrids was attempted.</description><subject>Animals</subject><subject>Biomedical and Life Sciences</subject><subject>Graft vs Host Reaction</subject><subject>Guinea Pigs - immunology</subject><subject>Immune Sera</subject><subject>Isoantigens</subject><subject>letters-to-editor</subject><subject>Life Sciences</subject><subject>Lymphocytes - immunology</subject><subject>Mice</subject><subject>Mice, Inbred A</subject><subject>Mice, Inbred C57BL</subject><subject>Spleen - cytology</subject><subject>Spleen - immunology</subject><issn>0090-0028</issn><issn>2058-1092</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1972</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kElLBDEQhYMoOi5Xb0IO4q21kt6SowxuMCC43IQmSVdrZDoZk7Qy_94eZhAUrEsd3vceVY-QYwbnDHJx4fBLW88L4KxQsEUmHEqRMZB8m0wAJGQAXOyR_RjfAXJW1HyX7BYFFJLBhLzcBNWl7BNDHGJ262OiD6hMsp82Lanv6GzZL968bekU5_NIrXuz2iZsqV7SS5dsFtD4V2eT9Y4-pjCYNASkjxiG_pDsdGoe8WizD8jz9dXT9Dab3d_cTS9nmclLmTJdQ1uVWHNdF2XXVrXQXV1XuapkLiXjwASgkrnSYjXayJZ1JRjRVpUsDeYH5Gyduwj-Y8CYmt5GM96rHPohNoKNnAA-gudr0AQfY8CuWQTbq7BsGDSrOpvfdY6Gk03yoHtsf_BNf6N-sdbjqLhXDM27H4Ibn_0_8XTtcGpV1E_iH-wbMsyOtA</recordid><startdate>19721213</startdate><enddate>19721213</enddate><creator>JOLLER, P. 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| ispartof | Nature. New biology (London), 1972-12, Vol.240 (102), p.214-215 |
| issn | 0090-0028 2058-1092 |
| language | eng |
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| source | MEDLINE; Nature Journals Online |
| subjects | Animals Biomedical and Life Sciences Graft vs Host Reaction Guinea Pigs - immunology Immune Sera Isoantigens letters-to-editor Life Sciences Lymphocytes - immunology Mice Mice, Inbred A Mice, Inbred C57BL Spleen - cytology Spleen - immunology |
| title | Graft-versus-Host Reactivity of Lymphoid Cells inhibited by Anti-recognition Structure Serum |
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