Influence of Compression Pressure and Velocity on Tablet Sticking

A rotary tablet machine fitted with 8-mm diameter flat-faced punches was used to measure scraper pressure (SCR), a type of shear stress, to evaluate sticking behavior. The shear stress between the surfaces of the tablet and lower punch was determined using an SCR detection system. Mean surface rough...

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Veröffentlicht in:	Chemical & Pharmaceutical Bulletin 2010/12/01, Vol.58(12), pp.1565-1568
Hauptverfasser:	Kakimi, Kazuyuki, Niwa, Toshiyuki, Danjo, Kazumi
Format:	Artikel
Sprache:	eng
Schlagworte:	adhesive force Adhesiveness compression pressure compression velocity Compressive Strength scraper pressure Shear Strength Surface Properties surface roughness Tablets - chemistry Technology, Pharmaceutical Tensile Strength
Online-Zugang:	Volltext
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