Prolonged giant cell excretion in severe African measles
This study reviews 54 Kenyan children with measles of varying severity. Children with severe measles and extensive staining of the skin had prolonged excretion of giant cells (presumably virus-containing) from their nasopharyngeal mucosa, ranging from 8 to 28 days after start of rash. Children with...
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| Veröffentlicht in: | Pediatrics (Evanston) 1972-12, Vol.50 (6), p.867-873 |
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| container_title | Pediatrics (Evanston) |
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| creator | Scheifele, D W Forbes, C E |
| description | This study reviews 54 Kenyan children with measles of varying severity. Children with severe measles and extensive staining of the skin had prolonged excretion of giant cells (presumably virus-containing) from their nasopharyngeal mucosa, ranging from 8 to 28 days after start of rash. Children with mild measles excreted giant cells for three days or less, conforming to the North American pattern of illness. Prolonged excretion of giant cells suggests an impaired cellular immune response in these children, which may be a function of their seriously impaired nutrition. |
| doi_str_mv | 10.1542/peds.50.6.867 |
| format | Article |
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Children with severe measles and extensive staining of the skin had prolonged excretion of giant cells (presumably virus-containing) from their nasopharyngeal mucosa, ranging from 8 to 28 days after start of rash. Children with mild measles excreted giant cells for three days or less, conforming to the North American pattern of illness. 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Prolonged excretion of giant cells suggests an impaired cellular immune response in these children, which may be a function of their seriously impaired nutrition.</description><subject>Child</subject><subject>Child Nutritional Physiological Phenomena</subject><subject>Child, Preschool</subject><subject>Humans</subject><subject>Infant</subject><subject>Kenya</subject><subject>Measles - complications</subject><subject>Measles - epidemiology</subject><subject>Measles - immunology</subject><subject>Measles - microbiology</subject><subject>Measles virus - isolation & purification</subject><subject>Mucous Membrane - pathology</subject><subject>Nasal Mucosa - microbiology</subject><subject>Nasal Mucosa - pathology</subject><subject>Nasopharynx - microbiology</subject><subject>Nasopharynx - pathology</subject><subject>Skin - immunology</subject><subject>Skin - pathology</subject><issn>0031-4005</issn><issn>1098-4275</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1972</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kDtLA0EURgdRYoyWlsJWdrveee6kDOILAlpoPczjTljZR5zZiP57NyRYfc3h43AIuaZQUSnY3RZDriRUqtKqPiFzCktdClbLUzIH4LQUAPKcXOT8CQBC1mxGZkJxJSSfE_2WhnboNxiKTWP7sfDYtgX--IRjM_RF0xcZvzFhsYqp8bYvOrS5xXxJzqJtM14dd0E-Hh_e75_L9evTy_1qXXqm9VhyKrRTLkxuSjHrHdWUcq-XLnrrnKzVNBAdC5yijzrWECRdWkZrB8EDX5Dbw-82DV87zKPpmryXtD0Ou2w0VTXTTE9geQB9GnJOGM02NZ1Nv4aC2Zcy-1JGglFmspn4m-PxznUY_uljGv4Hn-lkvw</recordid><startdate>197212</startdate><enddate>197212</enddate><creator>Scheifele, D W</creator><creator>Forbes, C E</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197212</creationdate><title>Prolonged giant cell excretion in severe African measles</title><author>Scheifele, D W ; Forbes, C E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c288t-3148b6bd867662acb18113c89bfcabb576cab0fb2d31ecf8f70d519a217b0dc03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1972</creationdate><topic>Child</topic><topic>Child Nutritional Physiological Phenomena</topic><topic>Child, Preschool</topic><topic>Humans</topic><topic>Infant</topic><topic>Kenya</topic><topic>Measles - complications</topic><topic>Measles - epidemiology</topic><topic>Measles - immunology</topic><topic>Measles - microbiology</topic><topic>Measles virus - isolation & purification</topic><topic>Mucous Membrane - pathology</topic><topic>Nasal Mucosa - microbiology</topic><topic>Nasal Mucosa - pathology</topic><topic>Nasopharynx - microbiology</topic><topic>Nasopharynx - pathology</topic><topic>Skin - immunology</topic><topic>Skin - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Scheifele, D W</creatorcontrib><creatorcontrib>Forbes, C E</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Pediatrics (Evanston)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Scheifele, D W</au><au>Forbes, C E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prolonged giant cell excretion in severe African measles</atitle><jtitle>Pediatrics (Evanston)</jtitle><addtitle>Pediatrics</addtitle><date>1972-12</date><risdate>1972</risdate><volume>50</volume><issue>6</issue><spage>867</spage><epage>873</epage><pages>867-873</pages><issn>0031-4005</issn><eissn>1098-4275</eissn><abstract>This study reviews 54 Kenyan children with measles of varying severity. 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| fulltext | fulltext |
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| ispartof | Pediatrics (Evanston), 1972-12, Vol.50 (6), p.867-873 |
| issn | 0031-4005 1098-4275 |
| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Child Child Nutritional Physiological Phenomena Child, Preschool Humans Infant Kenya Measles - complications Measles - epidemiology Measles - immunology Measles - microbiology Measles virus - isolation & purification Mucous Membrane - pathology Nasal Mucosa - microbiology Nasal Mucosa - pathology Nasopharynx - microbiology Nasopharynx - pathology Skin - immunology Skin - pathology |
| title | Prolonged giant cell excretion in severe African measles |
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