Serum PCSK9 is associated with multiple metabolic factors in a large Han Chinese population

Abstract Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a serine protease that regulates cholesterol metabolism through low-density lipoprotein receptor (LDLR) degradation. Gain-of-function and loss-of-function mutations within PCSK9 gene lead to hypercholesterolemia or hypocholesterolemia...

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Veröffentlicht in:	Atherosclerosis 2010-12, Vol.213 (2), p.632-636
Hauptverfasser:	Cui, Qin, Ju, Xianxia, Yang, Tao, Zhang, Mei, Tang, Wei, Chen, Qi, Hu, Yong, Haas, Joseph V, Troutt, Jason S, Pickard, Richard T, Darling, Ryan, Konrad, Robert J, Zhou, Hongwen, Cao, Guoqing
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Asian Continental Ancestry Group - genetics Atherosclerosis (general aspects, experimental research) Biological and medical sciences Biomarkers - blood Blood and lymphatic vessels Blood Glucose - metabolism Blood Pressure Cardiology. Vascular system Cardiovascular Cardiovascular Diseases - blood China Cholesterol - blood Cholesterol, LDL - blood Coronary heart disease Female Heart Humans Hypercholesterolemia LDL cholesterol LDL receptor Male Medical sciences Middle Aged PCSK9 Population-based study Postmenopause Proprotein Convertase 9 Proprotein Convertases Serine Endopeptidases - blood Serine Endopeptidases - genetics Triglycerides - blood
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