Metformin Versus Placebo from First Trimester to Delivery in Polycystic Ovary Syndrome: A Randomized, Controlled Multicenter Study

Context: Metformin is widely prescribed to pregnant women with polycystic ovary syndrome (PCOS) in an attempt to reduce pregnancy complications. Metformin is not approved for this indication, and evidence for this practice is lacking. Objectives: Our objective was to test the hypothesis that metform...

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Veröffentlicht in:	The journal of clinical endocrinology and metabolism 2010-12, Vol.95 (12), p.E448-E455
Hauptverfasser:	Vanky, Eszter, Stridsklev, Solhild, Heimstad, Runa, Romundstad, Pål, Skogøy, Kristin, Kleggetveit, Odrun, Hjelle, Sissel, von Brandis, Philip, Eikeland, Torunn, Flo, Karin, Berg, Kristin Flaten, Bunford, Gabor, Lund, Agnethe, Bjerke, Cecilie, Almås, Ingunn, Berg, Ann Hilde, Danielson, Anna, Lahmami, Gulim, Carlsen, Sven Magnus
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Blood Pressure Delivery, Obstetric Diabetes, Gestational - epidemiology Double-Blind Method Female Heart Rate Humans Metformin - therapeutic use Patient Compliance Placebos Polycystic Ovary Syndrome - drug therapy Pre-Eclampsia - drug therapy Pre-Eclampsia - epidemiology Pregnancy Pregnancy Complications - drug therapy Pregnancy Trimester, First - drug effects Pregnancy Trimester, First - physiology Random Allocation
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