Leukopenic and Thrombocytopenic Effect of Hypothermia in Dogs
Summary 1. Attention is drawn to the complication of impaired coagulation encountered in experimental hypothermia in dogs. 2. The method used for anesthetizing and rapidly reducing the body temperature by packing in cracked ice is described. 3. The following changes were associated with hypothermia:...
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| Veröffentlicht in: | Experimental biology and medicine (Maywood, N.J.) N.J.), 1955-11, Vol.90 (2), p.474-476 |
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| container_end_page | 476 |
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| container_issue | 2 |
| container_start_page | 474 |
| container_title | Experimental biology and medicine (Maywood, N.J.) |
| container_volume | 90 |
| creator | Helmsworth, James A. Stiles, William J. Elstun, Wesley |
| description | Summary
1. Attention is drawn to the complication of impaired coagulation encountered in experimental hypothermia in dogs. 2. The method used for anesthetizing and rapidly reducing the body temperature by packing in cracked ice is described. 3. The following changes were associated with hypothermia: The leukocyte count was reduced an average of 86%, the total eosinophil count was reduced an average of 86%; and the platelet count was reduced an average of 81%. 4. The coagulation mechanism was not studied directly, but data from these experiments suggest that the strong thrombocytopenic effect observed may be a factor in the impaired coagulation. |
| doi_str_mv | 10.3181/00379727-90-22070 |
| format | Article |
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1. Attention is drawn to the complication of impaired coagulation encountered in experimental hypothermia in dogs. 2. The method used for anesthetizing and rapidly reducing the body temperature by packing in cracked ice is described. 3. The following changes were associated with hypothermia: The leukocyte count was reduced an average of 86%, the total eosinophil count was reduced an average of 86%; and the platelet count was reduced an average of 81%. 4. The coagulation mechanism was not studied directly, but data from these experiments suggest that the strong thrombocytopenic effect observed may be a factor in the impaired coagulation.</description><identifier>ISSN: 0037-9727</identifier><identifier>ISSN: 1535-3702</identifier><identifier>EISSN: 1535-3699</identifier><identifier>DOI: 10.3181/00379727-90-22070</identifier><identifier>PMID: 13273485</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Animals ; Blood Platelets ; Body Temperature ; Dogs ; Hypothermia ; Leukocyte Count ; Leukocyte Disorders ; Leukopenia ; Old Medline</subject><ispartof>Experimental biology and medicine (Maywood, N.J.), 1955-11, Vol.90 (2), p.474-476</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c338t-4cdd345cc08d790864d920611775bb236b184ebc71647476d0bb3e6c74c20bbc3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,782,786,27931,27932</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/13273485$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Helmsworth, James A.</creatorcontrib><creatorcontrib>Stiles, William J.</creatorcontrib><creatorcontrib>Elstun, Wesley</creatorcontrib><title>Leukopenic and Thrombocytopenic Effect of Hypothermia in Dogs</title><title>Experimental biology and medicine (Maywood, N.J.)</title><addtitle>Proc Soc Exp Biol Med</addtitle><description>Summary
1. Attention is drawn to the complication of impaired coagulation encountered in experimental hypothermia in dogs. 2. The method used for anesthetizing and rapidly reducing the body temperature by packing in cracked ice is described. 3. The following changes were associated with hypothermia: The leukocyte count was reduced an average of 86%, the total eosinophil count was reduced an average of 86%; and the platelet count was reduced an average of 81%. 4. The coagulation mechanism was not studied directly, but data from these experiments suggest that the strong thrombocytopenic effect observed may be a factor in the impaired coagulation.</description><subject>Animals</subject><subject>Blood Platelets</subject><subject>Body Temperature</subject><subject>Dogs</subject><subject>Hypothermia</subject><subject>Leukocyte Count</subject><subject>Leukocyte Disorders</subject><subject>Leukopenia</subject><subject>Old Medline</subject><issn>0037-9727</issn><issn>1535-3702</issn><issn>1535-3699</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1955</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kD1PwzAQhi0EoqXwA1hQJrYUf8XnDAyoFIpUiaXMVuw4bUoTBzsZ8u9JaRAb053unnulexC6JXjOiCQPGDNIgUKc4phSDPgMTUnCkpiJND1H0-M-PgITdBXCHmOSABWXaEIYBcZlMkWPa9t9usbWpYmyOo82O-8q7UzfjsNlUVjTRq6IVn3j2p31VZlFZR09u224RhdFdgj2Zqwz9PGy3CxW8fr99W3xtI4NY7KNuclzxhNjsMwhxVLwPKVYEAKQaE2Z0ERyqw0QwYGDyLHWzAoD3NChNWyG7k-5jXdfnQ2tqspg7OGQ1dZ1QUkiqKQAA0hOoPEuBG8L1fiyynyvCFZHZ-rXmUqx-nE23NyN4Z2ubP53MUoagPkJCNnWqr3rfD08-0_iN0RGczA</recordid><startdate>195511</startdate><enddate>195511</enddate><creator>Helmsworth, James A.</creator><creator>Stiles, William J.</creator><creator>Elstun, Wesley</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>195511</creationdate><title>Leukopenic and Thrombocytopenic Effect of Hypothermia in Dogs</title><author>Helmsworth, James A. ; Stiles, William J. ; Elstun, Wesley</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c338t-4cdd345cc08d790864d920611775bb236b184ebc71647476d0bb3e6c74c20bbc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1955</creationdate><topic>Animals</topic><topic>Blood Platelets</topic><topic>Body Temperature</topic><topic>Dogs</topic><topic>Hypothermia</topic><topic>Leukocyte Count</topic><topic>Leukocyte Disorders</topic><topic>Leukopenia</topic><topic>Old Medline</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Helmsworth, James A.</creatorcontrib><creatorcontrib>Stiles, William J.</creatorcontrib><creatorcontrib>Elstun, Wesley</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Helmsworth, James A.</au><au>Stiles, William J.</au><au>Elstun, Wesley</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Leukopenic and Thrombocytopenic Effect of Hypothermia in Dogs</atitle><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle><addtitle>Proc Soc Exp Biol Med</addtitle><date>1955-11</date><risdate>1955</risdate><volume>90</volume><issue>2</issue><spage>474</spage><epage>476</epage><pages>474-476</pages><issn>0037-9727</issn><issn>1535-3702</issn><eissn>1535-3699</eissn><abstract>Summary
1. Attention is drawn to the complication of impaired coagulation encountered in experimental hypothermia in dogs. 2. The method used for anesthetizing and rapidly reducing the body temperature by packing in cracked ice is described. 3. The following changes were associated with hypothermia: The leukocyte count was reduced an average of 86%, the total eosinophil count was reduced an average of 86%; and the platelet count was reduced an average of 81%. 4. The coagulation mechanism was not studied directly, but data from these experiments suggest that the strong thrombocytopenic effect observed may be a factor in the impaired coagulation.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>13273485</pmid><doi>10.3181/00379727-90-22070</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0037-9727 |
| ispartof | Experimental biology and medicine (Maywood, N.J.), 1955-11, Vol.90 (2), p.474-476 |
| issn | 0037-9727 1535-3702 1535-3699 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_81628277 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Animals Blood Platelets Body Temperature Dogs Hypothermia Leukocyte Count Leukocyte Disorders Leukopenia Old Medline |
| title | Leukopenic and Thrombocytopenic Effect of Hypothermia in Dogs |
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