Growth of Leukemic Cells in Culture
Peripheral blood cells from three patients with leukemia in relapse increased in numbers in short-term suspension cultures. This increase was dependent on the presence of either feeder populations containing a high percentage of blast cells or conditioned medium derived from such populations. Aneupl...
Gespeichert in:
| Veröffentlicht in: | Blood 1972-12, Vol.40 (6), p.806-811 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 811 |
|---|---|
| container_issue | 6 |
| container_start_page | 806 |
| container_title | Blood |
| container_volume | 40 |
| creator | Aye, M.T. Till, J.E. McCulloch, E.A. |
| description | Peripheral blood cells from three patients with leukemia in relapse increased in numbers in short-term suspension cultures. This increase was dependent on the presence of either feeder populations containing a high percentage of blast cells or conditioned medium derived from such populations. Aneuploid cells present in direct marrow preparations were also prevalent in the cultures after 10 days. The apparent specificity of the increase for leukemic populations may provide a new approach to the study of leukemic blast cells. |
| doi_str_mv | 10.1182/blood.V40.6.806.806 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_81622314</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0006497120777001</els_id><sourcerecordid>81622314</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3146-4efa52343a53672c3093ae863e59f4eadc3fe0aa42565c0cf5da4d44c17f122c3</originalsourceid><addsrcrecordid>eNp9kE1Lw0AQhhdRaq3-AhECgrfE2c-kBw8StAoFL-p12W4muJp2626i-O_dfuDRw8sc5p13Zh5CzikUlFbsetF53xSvAgpVVLDVARlTyaocgMEhGQOAysW0pMfkJMZ3ACo4kyMyEhLKSskxuZwF_92_Zb7N5jh84NLZrMaui5lbZfXQ9UPAU3LUmi7i2b5OyMv93XP9kM-fZo_17Ty3nIq0B1sjGRfcSK5KZjlMucFKcZTTVqBpLG8RjBFMKmnBtrIxohHC0rKlLPkn5GqXuw7-c8DY66WLNh1jVuiHqCuqGEurkpHvjDb4GAO2eh3c0oQfTUFv0OgtGp3QaKUTlo3S1MU-flgssfmb2bNI_ZtdH9OPXw6DjtbhymLjAtpeN979m_8L8e9zsw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>81622314</pqid></control><display><type>article</type><title>Growth of Leukemic Cells in Culture</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Alma/SFX Local Collection</source><creator>Aye, M.T. ; Till, J.E. ; McCulloch, E.A.</creator><creatorcontrib>Aye, M.T. ; Till, J.E. ; McCulloch, E.A.</creatorcontrib><description>Peripheral blood cells from three patients with leukemia in relapse increased in numbers in short-term suspension cultures. This increase was dependent on the presence of either feeder populations containing a high percentage of blast cells or conditioned medium derived from such populations. Aneuploid cells present in direct marrow preparations were also prevalent in the cultures after 10 days. The apparent specificity of the increase for leukemic populations may provide a new approach to the study of leukemic blast cells.</description><identifier>ISSN: 0006-4971</identifier><identifier>EISSN: 1528-0020</identifier><identifier>DOI: 10.1182/blood.V40.6.806.806</identifier><identifier>PMID: 4507865</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Aneuploidy ; Cell Division ; Cells, Cultured ; Chromosome Aberrations ; Culture Media ; Humans ; Karyotyping ; Leukemia, Myeloid - blood ; Leukemia, Myeloid, Acute - blood ; Lymphocytes - cytology ; Methylcellulose</subject><ispartof>Blood, 1972-12, Vol.40 (6), p.806-811</ispartof><rights>1972 American Society of Hematology</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3146-4efa52343a53672c3093ae863e59f4eadc3fe0aa42565c0cf5da4d44c17f122c3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4507865$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Aye, M.T.</creatorcontrib><creatorcontrib>Till, J.E.</creatorcontrib><creatorcontrib>McCulloch, E.A.</creatorcontrib><title>Growth of Leukemic Cells in Culture</title><title>Blood</title><addtitle>Blood</addtitle><description>Peripheral blood cells from three patients with leukemia in relapse increased in numbers in short-term suspension cultures. This increase was dependent on the presence of either feeder populations containing a high percentage of blast cells or conditioned medium derived from such populations. Aneuploid cells present in direct marrow preparations were also prevalent in the cultures after 10 days. The apparent specificity of the increase for leukemic populations may provide a new approach to the study of leukemic blast cells.</description><subject>Aneuploidy</subject><subject>Cell Division</subject><subject>Cells, Cultured</subject><subject>Chromosome Aberrations</subject><subject>Culture Media</subject><subject>Humans</subject><subject>Karyotyping</subject><subject>Leukemia, Myeloid - blood</subject><subject>Leukemia, Myeloid, Acute - blood</subject><subject>Lymphocytes - cytology</subject><subject>Methylcellulose</subject><issn>0006-4971</issn><issn>1528-0020</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1972</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1Lw0AQhhdRaq3-AhECgrfE2c-kBw8StAoFL-p12W4muJp2626i-O_dfuDRw8sc5p13Zh5CzikUlFbsetF53xSvAgpVVLDVARlTyaocgMEhGQOAysW0pMfkJMZ3ACo4kyMyEhLKSskxuZwF_92_Zb7N5jh84NLZrMaui5lbZfXQ9UPAU3LUmi7i2b5OyMv93XP9kM-fZo_17Ty3nIq0B1sjGRfcSK5KZjlMucFKcZTTVqBpLG8RjBFMKmnBtrIxohHC0rKlLPkn5GqXuw7-c8DY66WLNh1jVuiHqCuqGEurkpHvjDb4GAO2eh3c0oQfTUFv0OgtGp3QaKUTlo3S1MU-flgssfmb2bNI_ZtdH9OPXw6DjtbhymLjAtpeN979m_8L8e9zsw</recordid><startdate>197212</startdate><enddate>197212</enddate><creator>Aye, M.T.</creator><creator>Till, J.E.</creator><creator>McCulloch, E.A.</creator><general>Elsevier Inc</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197212</creationdate><title>Growth of Leukemic Cells in Culture</title><author>Aye, M.T. ; Till, J.E. ; McCulloch, E.A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3146-4efa52343a53672c3093ae863e59f4eadc3fe0aa42565c0cf5da4d44c17f122c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1972</creationdate><topic>Aneuploidy</topic><topic>Cell Division</topic><topic>Cells, Cultured</topic><topic>Chromosome Aberrations</topic><topic>Culture Media</topic><topic>Humans</topic><topic>Karyotyping</topic><topic>Leukemia, Myeloid - blood</topic><topic>Leukemia, Myeloid, Acute - blood</topic><topic>Lymphocytes - cytology</topic><topic>Methylcellulose</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Aye, M.T.</creatorcontrib><creatorcontrib>Till, J.E.</creatorcontrib><creatorcontrib>McCulloch, E.A.</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Blood</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Aye, M.T.</au><au>Till, J.E.</au><au>McCulloch, E.A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Growth of Leukemic Cells in Culture</atitle><jtitle>Blood</jtitle><addtitle>Blood</addtitle><date>1972-12</date><risdate>1972</risdate><volume>40</volume><issue>6</issue><spage>806</spage><epage>811</epage><pages>806-811</pages><issn>0006-4971</issn><eissn>1528-0020</eissn><abstract>Peripheral blood cells from three patients with leukemia in relapse increased in numbers in short-term suspension cultures. This increase was dependent on the presence of either feeder populations containing a high percentage of blast cells or conditioned medium derived from such populations. Aneuploid cells present in direct marrow preparations were also prevalent in the cultures after 10 days. The apparent specificity of the increase for leukemic populations may provide a new approach to the study of leukemic blast cells.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>4507865</pmid><doi>10.1182/blood.V40.6.806.806</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0006-4971 |
| ispartof | Blood, 1972-12, Vol.40 (6), p.806-811 |
| issn | 0006-4971 1528-0020 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_81622314 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Aneuploidy Cell Division Cells, Cultured Chromosome Aberrations Culture Media Humans Karyotyping Leukemia, Myeloid - blood Leukemia, Myeloid, Acute - blood Lymphocytes - cytology Methylcellulose |
| title | Growth of Leukemic Cells in Culture |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T18%3A18%3A59IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Growth%20of%20Leukemic%20Cells%20in%20Culture&rft.jtitle=Blood&rft.au=Aye,%20M.T.&rft.date=1972-12&rft.volume=40&rft.issue=6&rft.spage=806&rft.epage=811&rft.pages=806-811&rft.issn=0006-4971&rft.eissn=1528-0020&rft_id=info:doi/10.1182/blood.V40.6.806.806&rft_dat=%3Cproquest_cross%3E81622314%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=81622314&rft_id=info:pmid/4507865&rft_els_id=S0006497120777001&rfr_iscdi=true |