Metabolism of C 19 -steroids by homogenates of normal rat and mouse adrenal tissue and of the Snell transplantable rat adrenocortical tumour 494

C(19)-steroid metabolism in homogenates of adrenal tissue from rats and mice has been studied. Production of these compounds from [7alpha-(3)H]cholesterol by rat adrenal tissue appeared to follow a route independent of pregnenolone. The major products of [7alpha-(3)H]-dehydroepiandrosterone metaboli...

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Veröffentlicht in:	Biochemical journal 1972-01, Vol.126 (1), p.99-106
Hauptverfasser:	Maynard, P V, Cameron, E H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Gland Neoplasms - metabolism Adrenal Glands - metabolism Androstanes - biosynthesis Androsterone - biosynthesis Animals Carbon Isotopes Cholesterol - metabolism Dehydroepiandrosterone - metabolism Etiocholanolone - biosynthesis In Vitro Techniques Ketones - biosynthesis Mice Neoplasms, Experimental - metabolism Pregnenolone - metabolism Rats Steroids - metabolism Tritium
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