p21cip/WAF is a key regulator of long-term radiation damage in mesenchyme-derived tissues

This study aimed to determine the mechanisms responsible for long-term tissue damage following radiation injury. We irradiated p21-knockout (p21⁻/⁻) and wild-type (WT) mice and determined the long-term deleterious effects of this intervention on mesenchyme-derived tissues. In addition, we explored t...

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Veröffentlicht in:The FASEB journal 2010-12, Vol.24 (12), p.4877-4888
Hauptverfasser: Mehrara, Babak J, Avraham, Tomer, Soares, Marc, Fernandez, John G, Yan, Alan, Zampell, Jamie C, Andrade, Victor P, Cordeiro, Andrew P, Sorrento, Cristina M
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Sprache:eng
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