Foam sclerotherapy using polidocanol for balloon-occluded retrograde transvenous obliteration (BRTO)

Purpose To evaluate the clinical safety and effectiveness of foam sclerotherapy using polidocanol for the treatment of gastric fundal varices by balloon-occluded retrograde transvenous obliteration (BRTO). Materials and methods From November 2005 to June 2009, foam sclerotherapy using polidocanol fo...

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Veröffentlicht in:European radiology 2011-01, Vol.21 (1), p.122-129
Hauptverfasser: Choi, Sun Young, Won, Jong Yun, Kim, Kyung Ah, Lee, Do Yun, Lee, Kwang-Hun
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container_issue 1
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container_title European radiology
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creator Choi, Sun Young
Won, Jong Yun
Kim, Kyung Ah
Lee, Do Yun
Lee, Kwang-Hun
description Purpose To evaluate the clinical safety and effectiveness of foam sclerotherapy using polidocanol for the treatment of gastric fundal varices by balloon-occluded retrograde transvenous obliteration (BRTO). Materials and methods From November 2005 to June 2009, foam sclerotherapy using polidocanol for the treatment of gastric fundal varices by BRTO was performed in 16 patients (male/female 11:5; age range 46–84 years, median 67 years). Foam was made of 3% polidocanol (Aethoxysklerol; Kreussler Pharma, Wiesbaden, Germany), room air, and contrast media, with a ratio of 1:2:1, respectively. The amount of polidocanol (2–24 mL; median 7 mL) depended on the volume of varices. Results Technical success was achieved in 15 of 16 patients (93.8%). Technical failure occurred in one patient. All patients were without pain during sclerotherapy. One patient experienced pulmonary edema after the procedure but completely recovered with medical treatment. There was no procedure-related mortality. Patients were followed by endoscopy, computed tomography, or both. Four patients were lost to follow-up. Clinical success was achieved in 10 of 11 patients (91%). Rebleeding occurred in one case during follow-up. Conclusions Foam sclerotherapy using polidocanol is clinically safe and effective for the treatment of gastric fundal varices during BRTO.
doi_str_mv 10.1007/s00330-010-1895-3
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Materials and methods From November 2005 to June 2009, foam sclerotherapy using polidocanol for the treatment of gastric fundal varices by BRTO was performed in 16 patients (male/female 11:5; age range 46–84 years, median 67 years). Foam was made of 3% polidocanol (Aethoxysklerol; Kreussler Pharma, Wiesbaden, Germany), room air, and contrast media, with a ratio of 1:2:1, respectively. The amount of polidocanol (2–24 mL; median 7 mL) depended on the volume of varices. Results Technical success was achieved in 15 of 16 patients (93.8%). Technical failure occurred in one patient. All patients were without pain during sclerotherapy. One patient experienced pulmonary edema after the procedure but completely recovered with medical treatment. There was no procedure-related mortality. Patients were followed by endoscopy, computed tomography, or both. Four patients were lost to follow-up. Clinical success was achieved in 10 of 11 patients (91%). Rebleeding occurred in one case during follow-up. Conclusions Foam sclerotherapy using polidocanol is clinically safe and effective for the treatment of gastric fundal varices during BRTO.</description><identifier>ISSN: 0938-7994</identifier><identifier>EISSN: 1432-1084</identifier><identifier>DOI: 10.1007/s00330-010-1895-3</identifier><identifier>PMID: 20737152</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer-Verlag</publisher><subject>Aged ; Aged, 80 and over ; Balloon Occlusion - standards ; Diagnostic Radiology ; Esophageal and Gastric Varices - therapy ; Female ; Gastrointestinal Hemorrhage - therapy ; Humans ; Imaging ; Internal Medicine ; Interventional ; Interventional Radiology ; Male ; Medicine ; Medicine &amp; Public Health ; Middle Aged ; Neuroradiology ; Polidocanol ; Polyethylene Glycols - therapeutic use ; Radiology ; Safety ; Sclerosing Solutions - standards ; Sclerosing Solutions - therapeutic use ; Sclerotherapy - standards ; Treatment Outcome ; Ultrasound</subject><ispartof>European radiology, 2011-01, Vol.21 (1), p.122-129</ispartof><rights>European Society of Radiology 2010</rights><rights>European Society of Radiology 2011</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c436t-baa9c339dab0ab7fa28e4b201c58ba4dfd6e52e4ecb0ca600976f54389bfd70c3</citedby><cites>FETCH-LOGICAL-c436t-baa9c339dab0ab7fa28e4b201c58ba4dfd6e52e4ecb0ca600976f54389bfd70c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00330-010-1895-3$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00330-010-1895-3$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20737152$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Choi, Sun Young</creatorcontrib><creatorcontrib>Won, Jong Yun</creatorcontrib><creatorcontrib>Kim, Kyung Ah</creatorcontrib><creatorcontrib>Lee, Do Yun</creatorcontrib><creatorcontrib>Lee, Kwang-Hun</creatorcontrib><title>Foam sclerotherapy using polidocanol for balloon-occluded retrograde transvenous obliteration (BRTO)</title><title>European radiology</title><addtitle>Eur Radiol</addtitle><addtitle>Eur Radiol</addtitle><description>Purpose To evaluate the clinical safety and effectiveness of foam sclerotherapy using polidocanol for the treatment of gastric fundal varices by balloon-occluded retrograde transvenous obliteration (BRTO). Materials and methods From November 2005 to June 2009, foam sclerotherapy using polidocanol for the treatment of gastric fundal varices by BRTO was performed in 16 patients (male/female 11:5; age range 46–84 years, median 67 years). Foam was made of 3% polidocanol (Aethoxysklerol; Kreussler Pharma, Wiesbaden, Germany), room air, and contrast media, with a ratio of 1:2:1, respectively. The amount of polidocanol (2–24 mL; median 7 mL) depended on the volume of varices. Results Technical success was achieved in 15 of 16 patients (93.8%). Technical failure occurred in one patient. All patients were without pain during sclerotherapy. One patient experienced pulmonary edema after the procedure but completely recovered with medical treatment. There was no procedure-related mortality. Patients were followed by endoscopy, computed tomography, or both. Four patients were lost to follow-up. Clinical success was achieved in 10 of 11 patients (91%). Rebleeding occurred in one case during follow-up. 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Materials and methods From November 2005 to June 2009, foam sclerotherapy using polidocanol for the treatment of gastric fundal varices by BRTO was performed in 16 patients (male/female 11:5; age range 46–84 years, median 67 years). Foam was made of 3% polidocanol (Aethoxysklerol; Kreussler Pharma, Wiesbaden, Germany), room air, and contrast media, with a ratio of 1:2:1, respectively. The amount of polidocanol (2–24 mL; median 7 mL) depended on the volume of varices. Results Technical success was achieved in 15 of 16 patients (93.8%). Technical failure occurred in one patient. All patients were without pain during sclerotherapy. One patient experienced pulmonary edema after the procedure but completely recovered with medical treatment. There was no procedure-related mortality. Patients were followed by endoscopy, computed tomography, or both. Four patients were lost to follow-up. Clinical success was achieved in 10 of 11 patients (91%). Rebleeding occurred in one case during follow-up. Conclusions Foam sclerotherapy using polidocanol is clinically safe and effective for the treatment of gastric fundal varices during BRTO.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer-Verlag</pub><pmid>20737152</pmid><doi>10.1007/s00330-010-1895-3</doi><tpages>8</tpages></addata></record>
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subjects Aged
Aged, 80 and over
Balloon Occlusion - standards
Diagnostic Radiology
Esophageal and Gastric Varices - therapy
Female
Gastrointestinal Hemorrhage - therapy
Humans
Imaging
Internal Medicine
Interventional
Interventional Radiology
Male
Medicine
Medicine & Public Health
Middle Aged
Neuroradiology
Polidocanol
Polyethylene Glycols - therapeutic use
Radiology
Safety
Sclerosing Solutions - standards
Sclerosing Solutions - therapeutic use
Sclerotherapy - standards
Treatment Outcome
Ultrasound
title Foam sclerotherapy using polidocanol for balloon-occluded retrograde transvenous obliteration (BRTO)
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