CARRIER STATE PREVALENCE OF HEPATITIS ASSOCIATED ANTIGEN (AU/SH) IN NIGERIA

Williams, A. O. (Univ. College Hospital, Ibadan, Nigeria), A. I . O. Williams, J. Buckels, J. A. Smith and T. I. Francis. Carrier state prevalence of hepatitis associated antigen (AU/SH) in Nigeria. Am J Epidemiol 96: 227–230, 1972.—Examinations of 1.574 sera from Nigerians by immunodiffusion for Au...

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Veröffentlicht in:American journal of epidemiology 1972-09, Vol.96 (3), p.227-230
Hauptverfasser: WILLIAMS, A. OLUFEMI, WILLIAMS, A. I. O., BUCKELS, J., SMITH, J. A., FRANCIS, T. I.
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container_issue 3
container_start_page 227
container_title American journal of epidemiology
container_volume 96
creator WILLIAMS, A. OLUFEMI
WILLIAMS, A. I. O.
BUCKELS, J.
SMITH, J. A.
FRANCIS, T. I.
description Williams, A. O. (Univ. College Hospital, Ibadan, Nigeria), A. I . O. Williams, J. Buckels, J. A. Smith and T. I. Francis. Carrier state prevalence of hepatitis associated antigen (AU/SH) in Nigeria. Am J Epidemiol 96: 227–230, 1972.—Examinations of 1.574 sera from Nigerians by immunodiffusion for Australia (Au) antigen revealed 84 (5.5%) positive individual carriers who are clinically well. This high prevalence rate confirms previous studies that the antigen occurs more frequently in populations in the tropics. The antigen is much more prevalent in the 21–30 year age groups in urban areas than in rural areas. Although the role of the antigen in chronic liver disease is not clear, it may be of considerable etiologic significance in the pathogenesis of liver diseases which are relatively common in the tropics. The exact mode of transmission remains obscure but scarification practices and arthropods, as transmitting vectors, may be of importance.
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This high prevalence rate confirms previous studies that the antigen occurs more frequently in populations in the tropics. The antigen is much more prevalent in the 21–30 year age groups in urban areas than in rural areas. Although the role of the antigen in chronic liver disease is not clear, it may be of considerable etiologic significance in the pathogenesis of liver diseases which are relatively common in the tropics. The exact mode of transmission remains obscure but scarification practices and arthropods, as transmitting vectors, may be of importance.</abstract><cop>United States</cop><pub>Oxford University Press</pub><pmid>4627077</pmid><doi>10.1093/oxfordjournals.aje.a121452</doi><tpages>4</tpages></addata></record>
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subjects Adolescent
Adult
Age Factors
Australia antigen
carrier state
Carrier State - microbiology
Child
Feces
Female
hepatitis
Hepatitis B Antigens
Humans
Immunodiffusion
Liver Diseases - immunology
Liver Function Tests
Male
Middle Aged
Nigeria
Rural Population
serology
Tropical Climate
Urban Population
title CARRIER STATE PREVALENCE OF HEPATITIS ASSOCIATED ANTIGEN (AU/SH) IN NIGERIA
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