Effect of diabetes on the clinical characteristics and prognosis of patients with chronic ischemic heart disease. The CIBAR study
The aim of this study was to evaluate the effect of diabetes mellitus on the prognosis of patients with chronic ischemic heart disease. The multicenter prospective cohort study involved 1108 outpatients with ischemic heart disease whose clinical characteristics were recorded by 69 primary care physi...
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| Veröffentlicht in: | Revista española de cardiologia 2010-11, Vol.63 (11), p.1371-1376 |
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| container_title | Revista española de cardiologia |
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| creator | Otero Raviña, Fernando Mazón-Ramos, Pilar Grigorian-Shamagian, Lilian Nores-Lorenzo, Augusto Zugaza-Gurruchaga, Lucrecia Seoane-Blanco, Rogelio Molina-Blanco, Angélica González-Juanatey, José R |
| description | The aim of this study was to evaluate the effect of diabetes mellitus on the prognosis of patients with chronic ischemic heart disease. The multicenter prospective cohort study involved 1108 outpatients with ischemic heart disease whose clinical characteristics were recorded by 69 primary care physicians. Morbidity and mortality were recorded during a mean follow-up period of 6.9 months. Overall, 29% of patients were diabetic; they were older than non-diabetics, presented with more risk factors, had poorer blood pressure control, and had more comorbid conditions. In addition, diabetics were more likely to be prescribed renin-angiotensin system blockers, calcium channel blockers, diuretics and lipid-lowering drugs. Cardiovascular mortality and hospitalization rates were higher in diabetics. On multivariate analysis, diabetes was found to be an independent predictor of a cardiovascular event (hazard ratio=1.81; 95% confidence interval, 1.17-2.82). Prognosis in chronic ischemic heart disease is relatively good, although it is worse in diabetics, which means that treatment and disease controls targets must be more rigorously applied in these patients. |
| doi_str_mv | 10.1016/S0300-8932(10)70307-9 |
| format | Article |
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The CIBAR study</title><source>MEDLINE</source><source>ScienceDirect Journals (5 years ago - present)</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>Otero Raviña, Fernando ; Mazón-Ramos, Pilar ; Grigorian-Shamagian, Lilian ; Nores-Lorenzo, Augusto ; Zugaza-Gurruchaga, Lucrecia ; Seoane-Blanco, Rogelio ; Molina-Blanco, Angélica ; González-Juanatey, José R</creator><creatorcontrib>Otero Raviña, Fernando ; Mazón-Ramos, Pilar ; Grigorian-Shamagian, Lilian ; Nores-Lorenzo, Augusto ; Zugaza-Gurruchaga, Lucrecia ; Seoane-Blanco, Rogelio ; Molina-Blanco, Angélica ; González-Juanatey, José R ; CIBAR Study investigators ; Barbanza Group</creatorcontrib><description>The aim of this study was to evaluate the effect of diabetes mellitus on the prognosis of patients with chronic ischemic heart disease. The multicenter prospective cohort study involved 1108 outpatients with ischemic heart disease whose clinical characteristics were recorded by 69 primary care physicians. Morbidity and mortality were recorded during a mean follow-up period of 6.9 months. Overall, 29% of patients were diabetic; they were older than non-diabetics, presented with more risk factors, had poorer blood pressure control, and had more comorbid conditions. In addition, diabetics were more likely to be prescribed renin-angiotensin system blockers, calcium channel blockers, diuretics and lipid-lowering drugs. Cardiovascular mortality and hospitalization rates were higher in diabetics. On multivariate analysis, diabetes was found to be an independent predictor of a cardiovascular event (hazard ratio=1.81; 95% confidence interval, 1.17-2.82). Prognosis in chronic ischemic heart disease is relatively good, although it is worse in diabetics, which means that treatment and disease controls targets must be more rigorously applied in these patients.</description><identifier>EISSN: 1579-2242</identifier><identifier>DOI: 10.1016/S0300-8932(10)70307-9</identifier><identifier>PMID: 21070733</identifier><language>eng ; spa</language><publisher>Spain</publisher><subject>Aged ; Chronic Disease ; Diabetes Complications - diagnosis ; Diabetes Complications - therapy ; Female ; Humans ; Male ; Myocardial Ischemia - diagnosis ; Myocardial Ischemia - therapy ; Prognosis ; Prospective Studies</subject><ispartof>Revista española de cardiologia, 2010-11, Vol.63 (11), p.1371-1376</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21070733$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Otero Raviña, Fernando</creatorcontrib><creatorcontrib>Mazón-Ramos, Pilar</creatorcontrib><creatorcontrib>Grigorian-Shamagian, Lilian</creatorcontrib><creatorcontrib>Nores-Lorenzo, Augusto</creatorcontrib><creatorcontrib>Zugaza-Gurruchaga, Lucrecia</creatorcontrib><creatorcontrib>Seoane-Blanco, Rogelio</creatorcontrib><creatorcontrib>Molina-Blanco, Angélica</creatorcontrib><creatorcontrib>González-Juanatey, José R</creatorcontrib><creatorcontrib>CIBAR Study investigators</creatorcontrib><creatorcontrib>Barbanza Group</creatorcontrib><title>Effect of diabetes on the clinical characteristics and prognosis of patients with chronic ischemic heart disease. The CIBAR study</title><title>Revista española de cardiologia</title><addtitle>Rev Esp Cardiol</addtitle><description>The aim of this study was to evaluate the effect of diabetes mellitus on the prognosis of patients with chronic ischemic heart disease. The multicenter prospective cohort study involved 1108 outpatients with ischemic heart disease whose clinical characteristics were recorded by 69 primary care physicians. Morbidity and mortality were recorded during a mean follow-up period of 6.9 months. Overall, 29% of patients were diabetic; they were older than non-diabetics, presented with more risk factors, had poorer blood pressure control, and had more comorbid conditions. In addition, diabetics were more likely to be prescribed renin-angiotensin system blockers, calcium channel blockers, diuretics and lipid-lowering drugs. Cardiovascular mortality and hospitalization rates were higher in diabetics. On multivariate analysis, diabetes was found to be an independent predictor of a cardiovascular event (hazard ratio=1.81; 95% confidence interval, 1.17-2.82). Prognosis in chronic ischemic heart disease is relatively good, although it is worse in diabetics, which means that treatment and disease controls targets must be more rigorously applied in these patients.</description><subject>Aged</subject><subject>Chronic Disease</subject><subject>Diabetes Complications - diagnosis</subject><subject>Diabetes Complications - therapy</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Myocardial Ischemia - diagnosis</subject><subject>Myocardial Ischemia - therapy</subject><subject>Prognosis</subject><subject>Prospective Studies</subject><issn>1579-2242</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1kE1LxDAQhoMg7rr6E5Tc1EM1X23a47qsurAg6HouaTKxkX7ZpMge_edGXE8zA8_78DIIXVBySwnN7l4JJyTJC86uKbmR8ZJJcYTmNJVFwphgM3Tq_QchLOVCnKAZo0QSyfkcfa-tBR1wb7FxqoIAHvcdDjVg3bjOadVgXatR6QCj88Fpj1Vn8DD2713vnf9NDio46ILHXy7UER_7GMTO6xrauNSgxhD1HpSHW7yL7tXmfvmCfZjM_gwdW9V4OD_MBXp7WO9WT8n2-XGzWm6TgQoSEiXSIksFFZkuBGUmtyK1UBVVnqnKZlUFYExqtVHCWFlJZqUtqOAcpGHWKr5AV3_eWP1zAh_KNjaEplEd9JMvc5qmQlIhI3l5IKeqBVMOo2vVuC__v8Z_AOrYcGg</recordid><startdate>201011</startdate><enddate>201011</enddate><creator>Otero Raviña, Fernando</creator><creator>Mazón-Ramos, Pilar</creator><creator>Grigorian-Shamagian, Lilian</creator><creator>Nores-Lorenzo, Augusto</creator><creator>Zugaza-Gurruchaga, Lucrecia</creator><creator>Seoane-Blanco, Rogelio</creator><creator>Molina-Blanco, Angélica</creator><creator>González-Juanatey, José R</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>201011</creationdate><title>Effect of diabetes on the clinical characteristics and prognosis of patients with chronic ischemic heart disease. 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In addition, diabetics were more likely to be prescribed renin-angiotensin system blockers, calcium channel blockers, diuretics and lipid-lowering drugs. Cardiovascular mortality and hospitalization rates were higher in diabetics. On multivariate analysis, diabetes was found to be an independent predictor of a cardiovascular event (hazard ratio=1.81; 95% confidence interval, 1.17-2.82). Prognosis in chronic ischemic heart disease is relatively good, although it is worse in diabetics, which means that treatment and disease controls targets must be more rigorously applied in these patients.</abstract><cop>Spain</cop><pmid>21070733</pmid><doi>10.1016/S0300-8932(10)70307-9</doi><tpages>6</tpages></addata></record> |
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| ispartof | Revista española de cardiologia, 2010-11, Vol.63 (11), p.1371-1376 |
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| source | MEDLINE; ScienceDirect Journals (5 years ago - present); EZB-FREE-00999 freely available EZB journals |
| subjects | Aged Chronic Disease Diabetes Complications - diagnosis Diabetes Complications - therapy Female Humans Male Myocardial Ischemia - diagnosis Myocardial Ischemia - therapy Prognosis Prospective Studies |
| title | Effect of diabetes on the clinical characteristics and prognosis of patients with chronic ischemic heart disease. The CIBAR study |
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