Biointerface by Cell Growth on Layered Graphene-Artificial Peroxidase-Protein Nanostructure for In Situ Quantitative Molecular Detection

A smart multifunctional biointerface with dimensional compatibility and good electrical conductivity is constructed by growing human breast adenocarcinoma cells on layered graphene–artificial peroxidase–extracellular matrix protein and further used to in situ selectively and quantatively detect reac...

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Veröffentlicht in:	Advanced materials (Weinheim) 2010-12, Vol.22 (45), p.5164-5167
Hauptverfasser:	Guo, Chun Xian, Zheng, Xin Ting, Lu, Zhi Song, Lou, Xiong Wen, Li, Chang Ming
Format:	Artikel
Sprache:	eng
Schlagworte:	biocompatible materials biomedical applications Biosensing Techniques - methods biosensors Cell Line, Tumor Cell Proliferation Graphite - chemistry Humans Hydrogen Peroxide - analysis Laminin - chemistry layered materials molecular recognition Nanostructures - chemistry Peroxidase - chemistry Sensitivity and Specificity Tissue Scaffolds - chemistry
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container_issue	45
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container_title	Advanced materials (Weinheim)
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creator	Guo, Chun Xian Zheng, Xin Ting Lu, Zhi Song Lou, Xiong Wen Li, Chang Ming
description	A smart multifunctional biointerface with dimensional compatibility and good electrical conductivity is constructed by growing human breast adenocarcinoma cells on layered graphene–artificial peroxidase–extracellular matrix protein and further used to in situ selectively and quantatively detect reactive oxygen species, for the first time discovering that the number of extracellular released hydrogen peroxide molecules is around 1011 per cell.
doi_str_mv	10.1002/adma.201001699
format	Article
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subjects	biocompatible materials biomedical applications Biosensing Techniques - methods biosensors Cell Line, Tumor Cell Proliferation Graphite - chemistry Humans Hydrogen Peroxide - analysis Laminin - chemistry layered materials molecular recognition Nanostructures - chemistry Peroxidase - chemistry Sensitivity and Specificity Tissue Scaffolds - chemistry
title	Biointerface by Cell Growth on Layered Graphene-Artificial Peroxidase-Protein Nanostructure for In Situ Quantitative Molecular Detection
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